2021 Mercedes-Benz S500 4matic MPG and Fuel Economy
On this page, you will find a complete guide to the miles per gallon and fuel efficiency data for the 2021 Mercedes-Benz S500 4matic.
The 2021 Mercedes-Benz S500 4matic has a 48V Li-Ion electric motor which is charged via standard charger.
All MPG estimates are "MPG equivalent". This is a conversion of electric energy consumption to a gasoline equivalent.
Whether you are considering a purchase of the car, or just wanting to find out how economical and environmentally friendly (or un-friendly) your 2021 Mercedes-Benz S500 4matic is, we have the information you need.
🛣 How Many Miles per Gallon (MPG) Does a 2021 Mercedes-Benz S500 4matic Get?
First off, the most commonly asked question. A 2021 Mercedes-Benz S500 4matic gets up to 20 miles per gallon in the city, and 29 miles per gallon on the highway.
The combined average MPG for the 2021 Mercedes-Benz S500 4matic is 24 miles per gallon.
💵 What is the Average Yearly Fuel Cost for a 2021 Mercedes-Benz S500 4matic?
The estimated fuel costs for the 2021 Mercedes-Benz S500 4matic is $3,100 per year.
That value has been estimated by government regulators based on 15,000 miles driven per year, using regular gasoline, and a split of 55% city driving and 45% highway driving.
If you were to compare a 2021 Mercedes-Benz S500 4matic to an average vehicle over 5 years, you will spend $4,000 more on fuel.
🛢 How Many Barrels of Petroleum Does a 2021 Mercedes-Benz S500 4matic Consume?
The 2021 Mercedes-Benz S500 4matic will consume roughly 12 barrels of petroleum per year, using the standard estimate of 15,000 miles per year.
The majority of the world's petroleum is sourced from countries like Saudi Arabia, Russia, Iraq, and the United States.
💨 How Many Grams of CO2 Does a 2021 Mercedes-Benz S500 4matic Emit?
For every mile driven, the 2021 Mercedes-Benz S500 4matic will emit 372 grams of CO2, which is about 5,580,000 grams of CO2 per year.
🌳 To help you understand the impact of this, a normal tree will absorb around 21,000 grams of CO2 per year. This means that roughly 190 trees would be needed to offset emissions from the 2021 Mercedes-Benz S500 4matic.
Overview
The table below covers all of the miles per gallon, engine specifications, and emission details we have for the 2021 Mercedes-Benz S500 4matic.
| City MPG | 20 |
|---|---|
| Highway MPG | 29 |
| Combined MPG | 24 |
| Save/Spend vs Average Car | Spend $4,000 |
| Fuel Cost | $3,100 |
| Fuel Type 1 | Premium |
| Electric Motor | 48V Li-Ion |
| ATV Type | Hybrid |
| Barrels of Petroleum | 12 |
| Grams of CO2 | 5,580,000 |
| Trees Needed to Offset | 266 |
| Drive | 4-Wheel Drive |
| Cylinders | 6 |
| Displacement | 3 |
| Transmission | Automatic 9-spd |
| Vehicle Class | Large Cars |
| Start/Stop? | Yes |
| Supercharged? | No |
| Turbocharged? | No |
Related Mercedes-Benz Models from 2021
If you're interested in other Mercedes-Benz models from 2021, you can find them in the table below. You can click the model link to find miles per gallon and emission information for that model.
Link To or Reference This Page
If you use this page in your research, please reference MPG Buddy as the source.
<a href="https://mpgbuddy.com/cars/mercedes-benz/s500-4matic/2021">2021 Mercedes-Benz S500 4matic MPG and Fuel Economy</a>
"2021 Mercedes-Benz S500 4matic MPG and Fuel Economy." MPG Buddy. Accessed on January 3, 2026. https://mpgbuddy.com/cars/mercedes-benz/s500-4matic/2021.
"2021 Mercedes-Benz S500 4matic MPG and Fuel Economy." MPG Buddy, https://mpgbuddy.com/cars/mercedes-benz/s500-4matic/2021. Accessed January 3, 2026.
2021 Mercedes-Benz S500 4matic MPG and Fuel Economy. MPG Buddy. Retrieved from https://mpgbuddy.com/cars/mercedes-benz/s500-4matic/2021.