Pick a year below to open the full Mercedes-Benz R500 page for that model year. Each year page covers combined, city, and highway MPG, the trim variants the EPA rates separately, the annual fuel cost across three driving patterns, and a year-over-year comparison so you can see whether the car has improved.

Fuel economy by model year

Combined MPG, city MPG, highway MPG, and the EPA's estimated annual fuel cost for every model year of the Mercedes-Benz R500. Click any year to see the full breakdown for that model year, including trim variants, the drivetrain, and a comparison against other vehicles in its segment.

Year Model Combined MPG City Highway Annual fuel cost
2006 2006 Mercedes-Benz R500 14 MPG 12 MPG 17 MPG $4,950

How the Mercedes-Benz R500 compares against the Sport Utility Vehicle - 4WD class

Buyers usually compare the Mercedes-Benz R500 against other cars in the same EPA class. The list below shows the most efficient cars in the Sport Utility Vehicle - 4WD class for the 2006 model year, the latest year on this page. Each link opens the full page for that car.

Source: U.S. EPA fuel economy dataset. Annual fuel cost assumes 15,000 miles of driving per year and a 55% city, 45% highway split.