2010 Mercedes-Benz C300: MPG and fuel economy
The 2010 Mercedes-Benz C300 is rated by the U.S. Environmental Protection Agency at 21 combined MPG, with 18 MPG in the city and 26 MPG on the highway. That sits a little below the average car in the Compact Cars class for the same model year.
This page collects every fuel-economy figure the EPA publishes for the 2010 Mercedes-Benz C300. Below you will find the headline combined, city, and highway MPG, the estimated annual fuel cost at three different driving levels, the tailpipe CO₂ emissions, and a full breakdown of the engine and drivetrain. The EPA rates 3 separate variants of this car (different engine, transmission, or drivetrain combinations), and you can compare them side by side in the trims table. If you want to know whether this generation got more or less efficient over the years, the year-over-year table further down covers every model year the EPA has rated.
Key takeaways
- The most efficient car in the Compact Cars class for the 2010 model year is the Honda Civic Hybrid at 42 MPG.
- The Mercedes-Benz C300 has gained 8 MPG since its first rated model year, the 2008 Mercedes-Benz C300 at 21 MPG.
- EPA estimates this car costs around $5,750 more in fuel over five years than an average new vehicle of the same model year.
- Requires premium gasoline, which typically adds about 40 to 60 cents per gallon to the EPA's annual fuel cost estimate.
Fuel economy at a glance
These are the EPA's official ratings for the 2010 Mercedes-Benz C300. The numbers come from a standardised laboratory test cycle and are the same figures that appear on the window sticker of every new car. Real-world mileage varies with driving style, weather, fuel quality, and how heavily loaded the car is.
When the EPA tests several variants of the same nameplate (for example, a front-wheel-drive version and an all-wheel-drive version), each gets its own rating. The figures shown here are the headline variant, taken as the configuration with the best combined MPG. The trims table further down covers all 3 variants side by side.
Combined MPG is a 55/45 weighted blend of the city and highway test cycles. The EPA uses it as the single number you can compare across the entire dataset, including hybrids and EVs (which use the equivalent MPGe figure).
| Combined MPG | 21 MPG |
| City MPG | 18 MPG |
| Highway MPG | 26 MPG |
| Annual fuel cost | $3,300 |
| Tailpipe CO₂ | 423 g/mi |
| Fuel type | Premium |
How the 2010 Mercedes-Benz C300 compares
The 2010 Mercedes-Benz C300 returns 21 combined MPG. Cars in the Compact Cars class for the same model year average 23 MPG, which puts this car behind the class average by about 9%.
The most efficient car in the Compact Cars class for the 2010 model year is the Honda Civic Hybrid at 42 MPG. The bar chart below puts the Mercedes-Benz C300 alongside the class best and the class average so you can see the full picture.
For broader context, the average new car of the 2010 model year (across all classes) returns 20.2 MPG. Larger vehicles pull the all-cars average down, so do not use that figure on its own to judge a small car or a hybrid. The full list of the most efficient cars of the 2010 model year is on its own page.
Trim variants rated for 2010
The EPA rates 3 separate variants of the 2010 Mercedes-Benz C300. The differences come from the engine size, transmission type, and drivetrain (front-wheel drive, all-wheel drive, and so on). The same nameplate can land several MPG apart depending on the configuration you actually buy.
| Engine and transmission | Drive | Combined | City | Highway | Annual cost |
|---|---|---|---|---|---|
| 3L, 6-cyl, Manual 6-spd | Rear-Wheel Drive | 21 MPG | 18 MPG | 26 MPG | $3,300 |
| 3L, 6-cyl, Automatic 7-spd | Rear-Wheel Drive | 21 MPG | 18 MPG | 26 MPG | $3,300 |
| 3.5L, 6-cyl, Automatic 7-spd | Rear-Wheel Drive | 21 MPG | 18 MPG | 26 MPG | $3,300 |
Annual fuel cost across driving patterns
The headline annual fuel cost the EPA publishes assumes 15,000 miles of driving per year and a fuel mix of 55% city and 45% highway. The dollar figure is calculated using the EPA's current reference price for premium gasoline, which is $4.61/gallon. EPA updates that reference periodically rather than tracking live pump prices, so treat it as a window-sticker estimate rather than today's pump number.
The table below scales the EPA's number to three common driving patterns. The combined MPG and the reference fuel price stay constant, only the annual mileage changes. To get a current-prices estimate, take your local gas price and multiply by 714.3 gallons (the car's annual consumption at the rated MPG).
| Driving pattern | Estimated annual fuel cost |
|---|---|
| Light driver, 7,500 miles per year | $1,650 |
| Average driver, 15,000 miles per year | $3,300 |
| Heavy driver, 25,000 miles per year | $5,500 |
Year-over-year MPG for the Mercedes-Benz C300
The EPA has rated the Mercedes-Benz C300 across 16 model years, from 2008 Mercedes-Benz C300 through 2026 Mercedes-Benz C300. The numbers below are the best combined MPG figure the EPA published for each year, which lets you see when the car was at its most efficient and how recent generations stack up.
The 2008 Mercedes-Benz C300 returned 21 MPG. The most recent 2026 Mercedes-Benz C300 returns 29 MPG. That is an improvement of 8 MPG over 18 model years, the kind of gain that usually comes from smaller engines, hybrid systems, or aerodynamic redesigns.
| Year | Combined MPG | Open year page |
|---|---|---|
| 2026 | 29 MPG | 2026 Mercedes-Benz C300 |
| 2025 | 29 MPG | 2025 Mercedes-Benz C300 |
| 2024 | 30 MPG | 2024 Mercedes-Benz C300 |
| 2023 | 29 MPG | 2023 Mercedes-Benz C300 |
| 2022 | 29 MPG | 2022 Mercedes-Benz C300 |
| 2021 | 27 MPG | 2021 Mercedes-Benz C300 |
| 2020 | 28 MPG | 2020 Mercedes-Benz C300 |
| 2019 | 27 MPG | 2019 Mercedes-Benz C300 |
| 2018 | 27 MPG | 2018 Mercedes-Benz C300 |
| 2017 | 28 MPG | 2017 Mercedes-Benz C300 |
| 2016 | 28 MPG | 2016 Mercedes-Benz C300 |
| 2015 | 28 MPG | 2015 Mercedes-Benz C300 |
| 2011 | 21 MPG | 2011 Mercedes-Benz C300 |
| 2010 | 21 MPG | this page |
| 2009 | 21 MPG | 2009 Mercedes-Benz C300 |
| 2008 | 21 MPG | 2008 Mercedes-Benz C300 |
Compare against other Compact Cars for 2010
If you are cross-shopping the 2010 Mercedes-Benz C300, the most useful comparison is against the other cars in the Compact Cars class for the same model year. The list below shows the highest-MPG peers, ranked from most to least efficient. Click any of them to open its full page.
The Honda Civic Hybrid leads this group at 42 MPG, 21 MPG ahead of the 2010 Mercedes-Benz C300.
Specifications
The 2010 Mercedes-Benz C300 runs a 3-liter 6-cylinder engine paired with a manual 6-spd, sending power through rear-wheel drive.
Engine, transmission, and drivetrain together drive most of the variation in fuel economy across trims. A larger engine moves the car with less effort but burns more fuel. A turbo lets a small engine punch above its weight, often without much MPG penalty. All-wheel drive adds traction and weight, and usually costs a couple of MPG compared with two-wheel drive of the same engine.
- Vehicle class
- Compact Cars
- Engine
- 3L 6-cylinder
- Transmission
- Manual 6-spd
- Drivetrain
- Rear-Wheel Drive
- Fuel type
- Premium
- Annual petroleum use
- 14.2 barrels per year
Common questions about the 2010 Mercedes-Benz C300
Quick answers to the questions people most often search for when looking up the 2010 Mercedes-Benz C300.
-
Is the 2010 Mercedes-Benz C300 fuel efficient?
It is in line with the rest of the class. The 2010 Mercedes-Benz C300 returns 21 combined MPG, and the average car in the Compact Cars class for the same model year sits at 23 MPG. -
What MPG does the 2010 Mercedes-Benz C300 get?
The EPA rates the 2010 Mercedes-Benz C300 at 21 combined MPG, 18 MPG in city driving, and 26 MPG on the highway. Real-world numbers depend on your driving style, the weather, and how loaded the car is. -
How much does it cost to fuel a 2010 Mercedes-Benz C300 per year?
The EPA estimates an annual fuel cost of $3,300 for the 2010 Mercedes-Benz C300. That figure assumes 15,000 miles of driving per year, a 55% city and 45% highway split, and the EPA's published average fuel price for the rated fuel grade. -
Does the 2010 Mercedes-Benz C300 require premium gas?
Yes. The EPA lists the 2010 Mercedes-Benz C300 as requiring premium gasoline. Running it on regular can reduce performance and may affect engine warranties, so it is not a recommended way to save at the pump. -
Has the Mercedes-Benz C300 become more fuel efficient over time?
Yes. The first EPA-rated Mercedes-Benz C300, the 2008 Mercedes-Benz C300, returned 21 combined MPG. The most recent 2026 Mercedes-Benz C300 returns 29 MPG, an improvement of 8 MPG over the run. -
How much CO₂ does the 2010 Mercedes-Benz C300 emit?
Tailpipe CO₂ emissions are 423 g/mi. Multiplied across a typical year of driving (15,000 miles) that works out to about 6,348 kilograms of CO₂. -
What is the difference between the city and highway MPG of the 2010 Mercedes-Benz C300?
City driving returns 18 MPG and highway driving returns 26 MPG, a gap of 8 MPG. A spread that wide is typical of cars with conventional automatic or manual transmissions, where stop-start city traffic eats more fuel than a steady highway cruise. -
What engine is in the 2010 Mercedes-Benz C300?
The 2010 Mercedes-Benz C300 has a 3-liter 6-cylinder engine (EPA description: PR). -
What transmission and drivetrain does the 2010 Mercedes-Benz C300 have?
The 2010 Mercedes-Benz C300 comes with a manual 6-spd transmission and rear-wheel drive. -
How does the 2010 Mercedes-Benz C300 compare to the best car in its class?
The most efficient car in the Compact Cars class for the 2010 model year is the Honda Civic Hybrid at 42 combined MPG. The Mercedes-Benz C300 returns 21 MPG, a gap of 21 MPG. If you are comparing on fuel economy alone, the class leader is worth a look.
Source: U.S. EPA fuel economy dataset. Annual fuel cost figures assume 15,000 miles of driving per year and a 55% city, 45% highway split. Real-world mileage varies with driving conditions, vehicle maintenance, fuel quality, and driver behaviour.