2022 Mercedes-Benz AMG GLE53 4matic Plus: MPG and fuel economy
The 2022 Mercedes-Benz AMG GLE53 4matic Plus is a hybrid rated at 19 combined MPG by the U.S. Environmental Protection Agency. It returns 18 MPG in the city and 22 MPG on the highway.
This page collects every fuel-economy figure the EPA publishes for the 2022 Mercedes-Benz AMG GLE53 4matic Plus. Below you will find the headline combined, city, and highway MPG, the estimated annual fuel cost at three different driving levels, the tailpipe CO₂ emissions, and a full breakdown of the engine and drivetrain. If you want to know whether this generation got more or less efficient over the years, the year-over-year table further down covers every model year the EPA has rated.
Key takeaways
- Returns 28% worse combined MPG than the average car in the Standard Sport Utility Vehicle 4WD class for the 2022 model year (26.3 MPG class average).
- The most efficient car in the Standard Sport Utility Vehicle 4WD class for the 2022 model year is the Tesla Model X at 102 MPG.
- EPA estimates this car costs around $7,500 more in fuel over five years than an average new vehicle of the same model year.
- Requires premium gasoline, which typically adds about 40 to 60 cents per gallon to the EPA's annual fuel cost estimate.
Fuel economy at a glance
These are the EPA's official ratings for the 2022 Mercedes-Benz AMG GLE53 4matic Plus. The numbers come from a standardised laboratory test cycle and are the same figures that appear on the window sticker of every new car. Real-world mileage varies with driving style, weather, fuel quality, and how heavily loaded the car is.
Combined MPG is a 55/45 weighted blend of the city and highway test cycles. The EPA uses it as the single number you can compare across the entire dataset, including hybrids and EVs (which use the equivalent MPGe figure).
| Combined MPG | 19 MPG |
| City MPG | 18 MPG |
| Highway MPG | 22 MPG |
| Annual fuel cost | $3,650 |
| Tailpipe CO₂ | 455 g/mi |
| Fuel type | Premium |
How the 2022 Mercedes-Benz AMG GLE53 4matic Plus compares
The 2022 Mercedes-Benz AMG GLE53 4matic Plus returns 19 combined MPG. Cars in the Standard Sport Utility Vehicle 4WD class for the same model year average 26.3 MPG, which puts this car behind the class average by about 28%.
The most efficient car in the Standard Sport Utility Vehicle 4WD class for the 2022 model year is the Tesla Model X at 102 MPG. The bar chart below puts the Mercedes-Benz AMG GLE53 4matic Plus alongside the class best and the class average so you can see the full picture.
For broader context, the average new car of the 2022 model year (across all classes) returns 30.7 MPG. Larger vehicles pull the all-cars average down, so do not use that figure on its own to judge a small car or a hybrid. The full list of the most efficient cars of the 2022 model year is on its own page.
Annual fuel cost across driving patterns
The headline annual fuel cost the EPA publishes assumes 15,000 miles of driving per year and a fuel mix of 55% city and 45% highway. The dollar figure is calculated using the EPA's current reference price for premium gasoline, which is $4.61/gallon. EPA updates that reference periodically rather than tracking live pump prices, so treat it as a window-sticker estimate rather than today's pump number.
The table below scales the EPA's number to three common driving patterns. The combined MPG and the reference fuel price stay constant, only the annual mileage changes. To get a current-prices estimate, take your local gas price and multiply by 789.5 gallons (the car's annual consumption at the rated MPG).
| Driving pattern | Estimated annual fuel cost |
|---|---|
| Light driver, 7,500 miles per year | $1,825 |
| Average driver, 15,000 miles per year | $3,650 |
| Heavy driver, 25,000 miles per year | $6,083 |
Year-over-year MPG for the Mercedes-Benz AMG GLE53 4matic Plus
The EPA has rated the Mercedes-Benz AMG GLE53 4matic Plus across 6 model years, from 2021 Mercedes-Benz AMG GLE53 4matic Plus through 2026 Mercedes-Benz AMG GLE53 4matic Plus. The numbers below are the best combined MPG figure the EPA published for each year, which lets you see when the car was at its most efficient and how recent generations stack up.
Combined MPG has stayed in roughly the same range across the run. The peak rating came with the 2024 Mercedes-Benz AMG GLE53 4matic Plus at 20 MPG.
| Year | Combined MPG | Open year page |
|---|---|---|
| 2026 | 20 MPG | 2026 Mercedes-Benz AMG GLE53 4matic Plus |
| 2025 | 20 MPG | 2025 Mercedes-Benz AMG GLE53 4matic Plus |
| 2024 | 20 MPG | 2024 Mercedes-Benz AMG GLE53 4matic Plus |
| 2023 | 19 MPG | 2023 Mercedes-Benz AMG GLE53 4matic Plus |
| 2022 | 19 MPG | this page |
| 2021 | 19 MPG | 2021 Mercedes-Benz AMG GLE53 4matic Plus |
Compare against other Standard Sport Utility Vehicle 4WD for 2022
If you are cross-shopping the 2022 Mercedes-Benz AMG GLE53 4matic Plus, the most useful comparison is against the other cars in the Standard Sport Utility Vehicle 4WD class for the same model year. The list below shows the highest-MPG peers, ranked from most to least efficient. Click any of them to open its full page.
The Tesla Model X leads this group at 102 MPG, 83 MPG ahead of the 2022 Mercedes-Benz AMG GLE53 4matic Plus.
Specifications
The 2022 Mercedes-Benz AMG GLE53 4matic Plus runs a 3-liter 6-cylinder engine paired with a automatic 9-spd, sending power through 4-wheel drive.
Engine, transmission, and drivetrain together drive most of the variation in fuel economy across trims. A larger engine moves the car with less effort but burns more fuel. A turbo lets a small engine punch above its weight, often without much MPG penalty. All-wheel drive adds traction and weight, and usually costs a couple of MPG compared with two-wheel drive of the same engine.
- Vehicle class
- Standard Sport Utility Vehicle 4WD
- Engine
- 3L 6-cylinder
- Transmission
- Automatic 9-spd
- Drivetrain
- 4-Wheel Drive
- Fuel type
- Premium
- Annual petroleum use
- 15.7 barrels per year
- Start-stop system
- Yes
Common questions about the 2022 Mercedes-Benz AMG GLE53 4matic Plus
Quick answers to the questions people most often search for when looking up the 2022 Mercedes-Benz AMG GLE53 4matic Plus.
-
Is the 2022 Mercedes-Benz AMG GLE53 4matic Plus fuel efficient?
Not particularly. The 2022 Mercedes-Benz AMG GLE53 4matic Plus returns 19 combined MPG, which trails the average car in the Standard Sport Utility Vehicle 4WD class for the same model year by about 28%. -
What MPG does the 2022 Mercedes-Benz AMG GLE53 4matic Plus get?
The EPA rates the 2022 Mercedes-Benz AMG GLE53 4matic Plus at 19 combined MPG, 18 MPG in city driving, and 22 MPG on the highway. Real-world numbers depend on your driving style, the weather, and how loaded the car is. -
How much does it cost to fuel a 2022 Mercedes-Benz AMG GLE53 4matic Plus per year?
The EPA estimates an annual fuel cost of $3,650 for the 2022 Mercedes-Benz AMG GLE53 4matic Plus. That figure assumes 15,000 miles of driving per year, a 55% city and 45% highway split, and the EPA's published average fuel price for the rated fuel grade. -
Does the 2022 Mercedes-Benz AMG GLE53 4matic Plus require premium gas?
Yes. The EPA lists the 2022 Mercedes-Benz AMG GLE53 4matic Plus as requiring premium gasoline. Running it on regular can reduce performance and may affect engine warranties, so it is not a recommended way to save at the pump. -
Has the Mercedes-Benz AMG GLE53 4matic Plus become more fuel efficient over time?
Combined MPG has stayed close to flat across the run. Both the earliest (2021 Mercedes-Benz AMG GLE53 4matic Plus, 19 MPG) and most recent (2026 Mercedes-Benz AMG GLE53 4matic Plus, 20 MPG) versions sit in the same range. -
How much CO₂ does the 2022 Mercedes-Benz AMG GLE53 4matic Plus emit?
Tailpipe CO₂ emissions are 455 g/mi. Multiplied across a typical year of driving (15,000 miles) that works out to about 6,825 kilograms of CO₂. -
What is the difference between the city and highway MPG of the 2022 Mercedes-Benz AMG GLE53 4matic Plus?
City driving returns 18 MPG and highway driving returns 22 MPG, a gap of 4 MPG. The two figures are close enough that the car will hold its rated efficiency well across most driving patterns. -
What engine is in the 2022 Mercedes-Benz AMG GLE53 4matic Plus?
The 2022 Mercedes-Benz AMG GLE53 4matic Plus has a 3-liter 6-cylinder engine (EPA description: SIDI; Mild Hybrid). -
What transmission and drivetrain does the 2022 Mercedes-Benz AMG GLE53 4matic Plus have?
The 2022 Mercedes-Benz AMG GLE53 4matic Plus comes with a automatic 9-spd transmission and 4-wheel drive. -
How does the 2022 Mercedes-Benz AMG GLE53 4matic Plus compare to the best car in its class?
The most efficient car in the Standard Sport Utility Vehicle 4WD class for the 2022 model year is the Tesla Model X at 102 combined MPG. The Mercedes-Benz AMG GLE53 4matic Plus returns 19 MPG, a gap of 83 MPG. If you are comparing on fuel economy alone, the class leader is worth a look.
Source: U.S. EPA fuel economy dataset. Annual fuel cost figures assume 15,000 miles of driving per year and a 55% city, 45% highway split. Real-world mileage varies with driving conditions, vehicle maintenance, fuel quality, and driver behaviour.