Pick a year below to open the full Mercedes-Benz AMG GLE53 4matic Plus page for that model year. Each year page covers combined, city, and highway MPG, the trim variants the EPA rates separately, the annual fuel cost across three driving patterns, and a year-over-year comparison so you can see whether the car has improved.

Fuel economy by model year

Combined MPG, city MPG, highway MPG, and the EPA's estimated annual fuel cost for every model year of the Mercedes-Benz AMG GLE53 4matic Plus. Click any year to see the full breakdown for that model year, including trim variants, the drivetrain, and a comparison against other vehicles in its segment.

Year Model Combined MPG City Highway Annual fuel cost
2026 2026 Mercedes-Benz AMG GLE53 4matic Plus 20 MPG 18 MPG 23 MPG $3,450
2025 2025 Mercedes-Benz AMG GLE53 4matic Plus 20 MPG 18 MPG 23 MPG $3,450
2024 2024 Mercedes-Benz AMG GLE53 4matic Plus 20 MPG 18 MPG 23 MPG $3,450
2023 2023 Mercedes-Benz AMG GLE53 4matic Plus 19 MPG 18 MPG 22 MPG $3,650
2022 2022 Mercedes-Benz AMG GLE53 4matic Plus 19 MPG 18 MPG 22 MPG $3,650
2021 2021 Mercedes-Benz AMG GLE53 4matic Plus 19 MPG 18 MPG 22 MPG $3,650

How the Mercedes-Benz AMG GLE53 4matic Plus compares against the Standard Sport Utility Vehicle 4WD class

Buyers usually compare the Mercedes-Benz AMG GLE53 4matic Plus against other cars in the same EPA class. The list below shows the most efficient cars in the Standard Sport Utility Vehicle 4WD class for the 2026 model year, the latest year on this page. Each link opens the full page for that car.

Source: U.S. EPA fuel economy dataset. Annual fuel cost assumes 15,000 miles of driving per year and a 55% city, 45% highway split.