Lexus RX 450h Plus AWD: MPG and fuel economy by year
The EPA has rated the Lexus RX 450h Plus AWD for one model year, the 2025 Lexus RX 450h Plus AWD. The most recent 2025 Lexus RX 450h Plus AWD returns 35 combined MPG.
Pick a year below to open the full Lexus RX 450h Plus AWD page for that model year. Each year page covers combined, city, and highway MPG, the trim variants the EPA rates separately, the annual fuel cost across three driving patterns, and a year-over-year comparison so you can see whether the car has improved.
Fuel economy by model year
Combined MPG, city MPG, highway MPG, and the EPA's estimated annual fuel cost for every model year of the Lexus RX 450h Plus AWD. Click any year to see the full breakdown for that model year, including trim variants, the drivetrain, and a comparison against other vehicles in its segment.
| Year | Model | Combined MPG | City | Highway | Annual fuel cost |
|---|---|---|---|---|---|
| 2025 | 2025 Lexus RX 450h Plus AWD | 35 MPG | 36 MPG | 33 MPG | $2,000 |
How the Lexus RX 450h Plus AWD compares against the Small Sport Utility Vehicle 4WD class
Buyers usually compare the Lexus RX 450h Plus AWD against other cars in the same EPA class. The list below shows the most efficient cars in the Small Sport Utility Vehicle 4WD class for the 2025 model year, the latest year on this page. Each link opens the full page for that car.
Source: U.S. EPA fuel economy dataset. Annual fuel cost assumes 15,000 miles of driving per year and a 55% city, 45% highway split.