Pick a year below to open the full Lexus RX 450h AWD page for that model year. Each year page covers combined, city, and highway MPG, the trim variants the EPA rates separately, the annual fuel cost across three driving patterns, and a year-over-year comparison so you can see whether the car has improved.

Fuel economy by model year

Combined MPG, city MPG, highway MPG, and the EPA's estimated annual fuel cost for every model year of the Lexus RX 450h AWD. Click any year to see the full breakdown for that model year, including trim variants, the drivetrain, and a comparison against other vehicles in its segment.

Year Model Combined MPG City Highway Annual fuel cost
2022 2022 Lexus RX 450h AWD 30 MPG 31 MPG 28 MPG $2,300
2021 2021 Lexus RX 450h AWD 30 MPG 31 MPG 28 MPG $2,300
2020 2020 Lexus RX 450h AWD 30 MPG 31 MPG 28 MPG $2,300
2019 2019 Lexus RX 450h AWD 30 MPG 31 MPG 28 MPG $2,300
2018 2018 Lexus RX 450h AWD 30 MPG 31 MPG 28 MPG $2,300
2017 2017 Lexus RX 450h AWD 30 MPG 31 MPG 28 MPG $2,300
2016 2016 Lexus RX 450h AWD 30 MPG 30 MPG 28 MPG $2,300
2015 2015 Lexus RX 450h AWD 28 MPG 29 MPG 27 MPG $2,450
2014 2014 Lexus RX 450h AWD 28 MPG 29 MPG 27 MPG $2,450
2013 2013 Lexus RX 450h AWD 28 MPG 29 MPG 27 MPG $2,450
2012 2012 Lexus RX 450h AWD 28 MPG 29 MPG 27 MPG $2,450
2011 2011 Lexus RX 450h AWD 28 MPG 29 MPG 27 MPG $2,450
2010 2010 Lexus RX 450h AWD 29 MPG 30 MPG 28 MPG $2,400

How the Lexus RX 450h AWD compares against the Standard Sport Utility Vehicle 4WD class

Buyers usually compare the Lexus RX 450h AWD against other cars in the same EPA class. The list below shows the most efficient cars in the Standard Sport Utility Vehicle 4WD class for the 2022 model year, the latest year on this page. Each link opens the full page for that car.

Source: U.S. EPA fuel economy dataset. Annual fuel cost assumes 15,000 miles of driving per year and a 55% city, 45% highway split.