Pick a year below to open the full Lexus NX 300 page for that model year. Each year page covers combined, city, and highway MPG, the trim variants the EPA rates separately, the annual fuel cost across three driving patterns, and a year-over-year comparison so you can see whether the car has improved.

Fuel economy by model year

Combined MPG, city MPG, highway MPG, and the EPA's estimated annual fuel cost for every model year of the Lexus NX 300. Click any year to see the full breakdown for that model year, including trim variants, the drivetrain, and a comparison against other vehicles in its segment.

Year Model Combined MPG City Highway Annual fuel cost
2021 2021 Lexus NX 300 25 MPG 22 MPG 28 MPG $2,750
2020 2020 Lexus NX 300 25 MPG 22 MPG 28 MPG $2,750
2019 2019 Lexus NX 300 25 MPG 22 MPG 28 MPG $2,750
2018 2018 Lexus NX 300 25 MPG 22 MPG 28 MPG $2,750

How the Lexus NX 300 compares against the Small Sport Utility Vehicle 2WD class

Buyers usually compare the Lexus NX 300 against other cars in the same EPA class. The list below shows the most efficient cars in the Small Sport Utility Vehicle 2WD class for the 2021 model year, the latest year on this page. Each link opens the full page for that car.

Source: U.S. EPA fuel economy dataset. Annual fuel cost assumes 15,000 miles of driving per year and a 55% city, 45% highway split.