Pick a year below to open the full Lexus GS 350 page for that model year. Each year page covers combined, city, and highway MPG, the trim variants the EPA rates separately, the annual fuel cost across three driving patterns, and a year-over-year comparison so you can see whether the car has improved.

Fuel economy by model year

Combined MPG, city MPG, highway MPG, and the EPA's estimated annual fuel cost for every model year of the Lexus GS 350. Click any year to see the full breakdown for that model year, including trim variants, the drivetrain, and a comparison against other vehicles in its segment.

Year Model Combined MPG City Highway Annual fuel cost
2020 2020 Lexus GS 350 23 MPG 20 MPG 28 MPG $3,000
2019 2019 Lexus GS 350 23 MPG 20 MPG 28 MPG $3,000
2018 2018 Lexus GS 350 23 MPG 20 MPG 28 MPG $3,000
2017 2017 Lexus GS 350 23 MPG 20 MPG 28 MPG $3,000
2016 2016 Lexus GS 350 23 MPG 20 MPG 28 MPG $3,000
2015 2015 Lexus GS 350 23 MPG 19 MPG 29 MPG $3,000
2014 2014 Lexus GS 350 23 MPG 19 MPG 29 MPG $3,000
2013 2013 Lexus GS 350 23 MPG 19 MPG 28 MPG $3,000
2011 2011 Lexus GS 350 21 MPG 19 MPG 26 MPG $3,300
2010 2010 Lexus GS 350 22 MPG 19 MPG 26 MPG $3,150
2009 2009 Lexus GS 350 22 MPG 19 MPG 26 MPG $3,150
2008 2008 Lexus GS 350 22 MPG 19 MPG 27 MPG $3,150
2007 2007 Lexus GS 350 22 MPG 19 MPG 26 MPG $3,150

How the Lexus GS 350 compares against the Midsize Cars class

Buyers usually compare the Lexus GS 350 against other cars in the same EPA class. The list below shows the most efficient cars in the Midsize Cars class for the 2020 model year, the latest year on this page. Each link opens the full page for that car.

Source: U.S. EPA fuel economy dataset. Annual fuel cost assumes 15,000 miles of driving per year and a 55% city, 45% highway split.