Pick a year below to open the full Infiniti QX80 2WD page for that model year. Each year page covers combined, city, and highway MPG, the trim variants the EPA rates separately, the annual fuel cost across three driving patterns, and a year-over-year comparison so you can see whether the car has improved.

Fuel economy by model year

Combined MPG, city MPG, highway MPG, and the EPA's estimated annual fuel cost for every model year of the Infiniti QX80 2WD. Click any year to see the full breakdown for that model year, including trim variants, the drivetrain, and a comparison against other vehicles in its segment.

Year Model Combined MPG City Highway Annual fuel cost
2026 2026 Infiniti QX80 2WD 18 MPG 16 MPG 20 MPG $3,850
2025 2025 Infiniti QX80 2WD 18 MPG 16 MPG 20 MPG $3,850
2024 2024 Infiniti QX80 2WD 16 MPG 14 MPG 20 MPG $4,300
2023 2023 Infiniti QX80 2WD 16 MPG 14 MPG 20 MPG $4,300
2022 2022 Infiniti QX80 2WD 16 MPG 14 MPG 20 MPG $4,300
2021 2021 Infiniti QX80 2WD 16 MPG 14 MPG 20 MPG $4,300
2020 2020 Infiniti QX80 2WD 16 MPG 14 MPG 20 MPG $4,300
2019 2019 Infiniti QX80 2WD 16 MPG 14 MPG 20 MPG $4,300
2018 2018 Infiniti QX80 2WD 16 MPG 14 MPG 20 MPG $4,300
2017 2017 Infiniti QX80 2WD 16 MPG 14 MPG 20 MPG $4,300
2016 2016 Infiniti QX80 2WD 16 MPG 14 MPG 20 MPG $4,300
2015 2015 Infiniti QX80 2WD 16 MPG 14 MPG 20 MPG $4,300
2014 2014 Infiniti QX80 2WD 16 MPG 14 MPG 20 MPG $4,300

How the Infiniti QX80 2WD compares against the Standard Sport Utility Vehicle 2WD class

Buyers usually compare the Infiniti QX80 2WD against other cars in the same EPA class. The list below shows the most efficient cars in the Standard Sport Utility Vehicle 2WD class for the 2026 model year, the latest year on this page. Each link opens the full page for that car.

Source: U.S. EPA fuel economy dataset. Annual fuel cost assumes 15,000 miles of driving per year and a 55% city, 45% highway split.