Pick a year below to open the full Audi S6 page for that model year. Each year page covers combined, city, and highway MPG, the trim variants the EPA rates separately, the annual fuel cost across three driving patterns, and a year-over-year comparison so you can see whether the car has improved.

Fuel economy by model year

Combined MPG, city MPG, highway MPG, and the EPA's estimated annual fuel cost for every model year of the Audi S6. Click any year to see the full breakdown for that model year, including trim variants, the drivetrain, and a comparison against other vehicles in its segment.

Year Model Combined MPG City Highway Annual fuel cost
2025 2025 Audi S6 22 MPG 19 MPG 27 MPG $3,150
2024 2024 Audi S6 22 MPG 19 MPG 26 MPG $3,150
2023 2023 Audi S6 22 MPG 19 MPG 26 MPG $3,150
2022 2022 Audi S6 22 MPG 18 MPG 28 MPG $3,150
2021 2021 Audi S6 22 MPG 18 MPG 28 MPG $3,150
2020 2020 Audi S6 22 MPG 18 MPG 28 MPG $3,150
2018 2018 Audi S6 18 MPG 16 MPG 24 MPG $3,850
2017 2017 Audi S6 21 MPG 18 MPG 27 MPG $3,300
2016 2016 Audi S6 21 MPG 18 MPG 27 MPG $3,300
2015 2015 Audi S6 20 MPG 17 MPG 27 MPG $3,450
2014 2014 Audi S6 20 MPG 17 MPG 27 MPG $3,450
2013 2013 Audi S6 20 MPG 17 MPG 27 MPG $3,450
2011 2011 Audi S6 16 MPG 14 MPG 21 MPG $4,300
2010 2010 Audi S6 16 MPG 14 MPG 19 MPG $4,300
2009 2009 Audi S6 16 MPG 14 MPG 19 MPG $4,300
2008 2008 Audi S6 16 MPG 14 MPG 19 MPG $4,300
2007 2007 Audi S6 16 MPG 14 MPG 19 MPG $4,300
1995 1995 Audi S6 18 MPG 16 MPG 22 MPG $3,850

How the Audi S6 compares against the Midsize Cars class

Buyers usually compare the Audi S6 against other cars in the same EPA class. The list below shows the most efficient cars in the Midsize Cars class for the 2025 model year, the latest year on this page. Each link opens the full page for that car.

Source: U.S. EPA fuel economy dataset. Annual fuel cost assumes 15,000 miles of driving per year and a 55% city, 45% highway split.