2006 Nissan Altima: MPG and fuel economy

This page collects every fuel-economy figure the EPA publishes for the 2006 Nissan Altima. Below you will find the headline combined, city, and highway MPG, the estimated annual fuel cost at three different driving levels, the tailpipe CO₂ emissions, and a full breakdown of the engine and drivetrain. The EPA rates 5 separate variants of this car (different engine, transmission, or drivetrain combinations), and you can compare them side by side in the trims table. If you want to know whether this generation got more or less efficient over the years, the year-over-year table further down covers every model year the EPA has rated.

Fuel economy at a glance

These are the EPA's official ratings for the 2006 Nissan Altima. The numbers come from a standardised laboratory test cycle and are the same figures that appear on the window sticker of every new car. Real-world mileage varies with driving style, weather, fuel quality, and how heavily loaded the car is.

When the EPA tests several variants of the same nameplate (for example, a front-wheel-drive version and an all-wheel-drive version), each gets its own rating. The figures shown here are the headline variant, taken as the configuration with the best combined MPG. The trims table further down covers all 5 variants side by side.

Combined MPG is a 55/45 weighted blend of the city and highway test cycles. The EPA uses it as the single number you can compare across the entire dataset, including hybrids and EVs (which use the equivalent MPGe figure).

How the 2006 Nissan Altima compares

The 2006 Nissan Altima returns 24 combined MPG. Cars in the Midsize Cars class for the same model year average 20.3 MPG, which puts this car ahead of the class average by about 18%.

The most efficient car in the Midsize Cars class for the 2006 model year is the Toyota Prius at 46 MPG. The bar chart below puts the Nissan Altima alongside the class best and the class average so you can see the full picture.

For broader context, the average new car of the 2006 model year (across all classes) returns 18.6 MPG. Larger vehicles pull the all-cars average down, so do not use that figure on its own to judge a small car or a hybrid. The full list of the most efficient cars of the 2006 model year is on its own page.

Trim variants rated for 2006

The EPA rates 5 separate variants of the 2006 Nissan Altima. The differences come from the engine size, transmission type, and drivetrain (front-wheel drive, all-wheel drive, and so on). The same nameplate can land several MPG apart depending on the configuration you actually buy.

Annual fuel cost across driving patterns

The headline annual fuel cost the EPA publishes assumes 15,000 miles of driving per year and a fuel mix of 55% city and 45% highway. The dollar figure is calculated using the EPA's current reference price for regular gasoline, which is $3.99/gallon. EPA updates that reference periodically rather than tracking live pump prices, so treat it as a window-sticker estimate rather than today's pump number.

The table below scales the EPA's number to three common driving patterns. The combined MPG and the reference fuel price stay constant, only the annual mileage changes. To get a current-prices estimate, take your local gas price and multiply by 625 gallons (the car's annual consumption at the rated MPG).

Year-over-year MPG for the Nissan Altima

The EPA has rated the Nissan Altima across 29 model years, from 1998 Nissan Altima through 2026 Nissan Altima. The numbers below are the best combined MPG figure the EPA published for each year, which lets you see when the car was at its most efficient and how recent generations stack up.

The 1998 Nissan Altima returned 24 MPG. The most recent 2026 Nissan Altima returns 30 MPG. That is an improvement of 6 MPG over 28 model years, the kind of gain that usually comes from smaller engines, hybrid systems, or aerodynamic redesigns.

Compare against other Midsize Cars for 2006

If you are cross-shopping the 2006 Nissan Altima, the most useful comparison is against the other cars in the Midsize Cars class for the same model year. The list below shows the highest-MPG peers, ranked from most to least efficient. Click any of them to open its full page.

The Toyota Prius leads this group at 46 MPG, 22 MPG ahead of the 2006 Nissan Altima.

Specifications

The 2006 Nissan Altima runs a 2.5-liter 4-cylinder engine paired with a manual 5-spd, sending power through front-wheel drive.

Engine, transmission, and drivetrain together drive most of the variation in fuel economy across trims. A larger engine moves the car with less effort but burns more fuel. A turbo lets a small engine punch above its weight, often without much MPG penalty. All-wheel drive adds traction and weight, and usually costs a couple of MPG compared with two-wheel drive of the same engine.

Vehicle class

Midsize Cars

Engine

2.5L 4-cylinder

Transmission

Manual 5-spd

Drivetrain

Front-Wheel Drive

Fuel type

Regular

Annual petroleum use

12.4 barrels per year

Common questions about the 2006 Nissan Altima

Quick answers to the questions people most often search for when looking up the 2006 Nissan Altima.

• Is the 2006 Nissan Altima fuel efficient?

  Yes. The 2006 Nissan Altima returns 24 combined MPG, which beats the average car in the Midsize Cars class for the same model year by about 18%.
• What MPG does the 2006 Nissan Altima get?

  The EPA rates the 2006 Nissan Altima at 24 combined MPG, 21 MPG in city driving, and 29 MPG on the highway. Real-world numbers depend on your driving style, the weather, and how loaded the car is.
• How much does it cost to fuel a 2006 Nissan Altima per year?

  The EPA estimates an annual fuel cost of $2,500 for the 2006 Nissan Altima. That figure assumes 15,000 miles of driving per year, a 55% city and 45% highway split, and the EPA's published average fuel price for the rated fuel grade.
• What fuel does the 2006 Nissan Altima use?

  The EPA lists the 2006 Nissan Altima as running on regular gasoline. Using a different grade than the manufacturer specifies can affect fuel economy and engine longevity.
• Has the Nissan Altima become more fuel efficient over time?

  Yes. The first EPA-rated Nissan Altima, the 1998 Nissan Altima, returned 24 combined MPG. The most recent 2026 Nissan Altima returns 30 MPG, an improvement of 6 MPG over the run.
• How much CO₂ does the 2006 Nissan Altima emit?

  Tailpipe CO₂ emissions are 370 g/mi. Multiplied across a typical year of driving (15,000 miles) that works out to about 5,554 kilograms of CO₂.
• What is the difference between the city and highway MPG of the 2006 Nissan Altima?

  City driving returns 21 MPG and highway driving returns 29 MPG, a gap of 8 MPG. A spread that wide is typical of cars with conventional automatic or manual transmissions, where stop-start city traffic eats more fuel than a steady highway cruise.
• What engine is in the 2006 Nissan Altima?

  The 2006 Nissan Altima has a 2.5-liter 4-cylinder engine.
• What transmission and drivetrain does the 2006 Nissan Altima have?

  The 2006 Nissan Altima comes with a manual 5-spd transmission and front-wheel drive.
• How does the 2006 Nissan Altima compare to the best car in its class?

  The most efficient car in the Midsize Cars class for the 2006 model year is the Toyota Prius at 46 combined MPG. The Nissan Altima returns 24 MPG, a gap of 22 MPG. If you are comparing on fuel economy alone, the class leader is worth a look.

Source: U.S. EPA fuel economy dataset. Annual fuel cost figures assume 15,000 miles of driving per year and a 55% city, 45% highway split. Real-world mileage varies with driving conditions, vehicle maintenance, fuel quality, and driver behaviour.