Pick a year below to open the full Mercedes-Benz S550 page for that model year. Each year page covers combined, city, and highway MPG, the trim variants the EPA rates separately, the annual fuel cost across three driving patterns, and a year-over-year comparison so you can see whether the car has improved.

Fuel economy by model year

Combined MPG, city MPG, highway MPG, and the EPA's estimated annual fuel cost for every model year of the Mercedes-Benz S550. Click any year to see the full breakdown for that model year, including trim variants, the drivetrain, and a comparison against other vehicles in its segment.

Year Model Combined MPG City Highway Annual fuel cost
2017 2017 Mercedes-Benz S550 21 MPG 18 MPG 26 MPG $3,300
2016 2016 Mercedes-Benz S550 20 MPG 17 MPG 26 MPG $3,450
2015 2015 Mercedes-Benz S550 20 MPG 17 MPG 26 MPG $3,450
2014 2014 Mercedes-Benz S550 20 MPG 17 MPG 26 MPG $3,450
2013 2013 Mercedes-Benz S550 19 MPG 15 MPG 25 MPG $3,650
2012 2012 Mercedes-Benz S550 19 MPG 15 MPG 25 MPG $3,650
2011 2011 Mercedes-Benz S550 18 MPG 15 MPG 23 MPG $3,850
2010 2010 Mercedes-Benz S550 18 MPG 15 MPG 23 MPG $3,850
2009 2009 Mercedes-Benz S550 17 MPG 14 MPG 22 MPG $4,050
2008 2008 Mercedes-Benz S550 16 MPG 14 MPG 21 MPG $4,300
2007 2007 Mercedes-Benz S550 17 MPG 14 MPG 22 MPG $4,050

How the Mercedes-Benz S550 compares against the Large Cars class

Buyers usually compare the Mercedes-Benz S550 against other cars in the same EPA class. The list below shows the most efficient cars in the Large Cars class for the 2017 model year, the latest year on this page. Each link opens the full page for that car.

Source: U.S. EPA fuel economy dataset. Annual fuel cost assumes 15,000 miles of driving per year and a 55% city, 45% highway split.