Pick a year below to open the full Mercedes-Benz S430 page for that model year. Each year page covers combined, city, and highway MPG, the trim variants the EPA rates separately, the annual fuel cost across three driving patterns, and a year-over-year comparison so you can see whether the car has improved.

Fuel economy by model year

Combined MPG, city MPG, highway MPG, and the EPA's estimated annual fuel cost for every model year of the Mercedes-Benz S430. Click any year to see the full breakdown for that model year, including trim variants, the drivetrain, and a comparison against other vehicles in its segment.

Year Model Combined MPG City Highway Annual fuel cost
2006 2006 Mercedes-Benz S430 19 MPG 16 MPG 24 MPG $3,650
2005 2005 Mercedes-Benz S430 19 MPG 16 MPG 24 MPG $3,650
2004 2004 Mercedes-Benz S430 19 MPG 16 MPG 24 MPG $3,650
2003 2003 Mercedes-Benz S430 18 MPG 15 MPG 22 MPG $3,850
2002 2002 Mercedes-Benz S430 18 MPG 15 MPG 22 MPG $3,850
2001 2001 Mercedes-Benz S430 18 MPG 16 MPG 23 MPG $3,850
2000 2000 Mercedes-Benz S430 18 MPG 15 MPG 22 MPG $3,850

How the Mercedes-Benz S430 compares against the Large Cars class

Buyers usually compare the Mercedes-Benz S430 against other cars in the same EPA class. The list below shows the most efficient cars in the Large Cars class for the 2006 model year, the latest year on this page. Each link opens the full page for that car.

Source: U.S. EPA fuel economy dataset. Annual fuel cost assumes 15,000 miles of driving per year and a 55% city, 45% highway split.