Mercedes-Benz EQS 450 Plus: MPG and fuel economy by year
The EPA has rated the Mercedes-Benz EQS 450 Plus across 4 model years, from the 2022 Mercedes-Benz EQS 450 Plus through the 2026 Mercedes-Benz EQS 450 Plus. The most recent 2026 Mercedes-Benz EQS 450 Plus returns 98 combined MPG.
Pick a year below to open the full Mercedes-Benz EQS 450 Plus page for that model year. Each year page covers combined, city, and highway MPG, the trim variants the EPA rates separately, the annual fuel cost across three driving patterns, and a year-over-year comparison so you can see whether the car has improved.
Fuel economy by model year
Combined MPG, city MPG, highway MPG, and the EPA's estimated annual fuel cost for every model year of the Mercedes-Benz EQS 450 Plus. Click any year to see the full breakdown for that model year, including trim variants, the drivetrain, and a comparison against other vehicles in its segment.
| Year | Model | Combined MPG | City | Highway | Annual fuel cost |
|---|---|---|---|---|---|
| 2026 | 2026 Mercedes-Benz EQS 450 Plus | 98 MPG | 98 MPG | 98 MPG | $750 |
| 2025 | 2025 Mercedes-Benz EQS 450 Plus | 98 MPG | 98 MPG | 98 MPG | $750 |
| 2024 | 2024 Mercedes-Benz EQS 450 Plus | 96 MPG | 95 MPG | 98 MPG | $800 |
| 2022 | 2022 Mercedes-Benz EQS 450 Plus | 97 MPG | 97 MPG | 97 MPG | $800 |
How the Mercedes-Benz EQS 450 Plus compares against the Large Cars class
Buyers usually compare the Mercedes-Benz EQS 450 Plus against other cars in the same EPA class. The list below shows the most efficient cars in the Large Cars class for the 2026 model year, the latest year on this page. Each link opens the full page for that car.
Source: U.S. EPA fuel economy dataset. Annual fuel cost assumes 15,000 miles of driving per year and a 55% city, 45% highway split.