Mercedes-Benz E450 4matic (station wagon): MPG and fuel economy by year
The EPA has rated the Mercedes-Benz E450 4matic (station wagon) across 2 model years, from the 2019 Mercedes-Benz E450 4matic (station wagon) through the 2020 Mercedes-Benz E450 4matic (station wagon). The most recent 2020 Mercedes-Benz E450 4matic (station wagon) returns 22 combined MPG.
Pick a year below to open the full Mercedes-Benz E450 4matic (station wagon) page for that model year. Each year page covers combined, city, and highway MPG, the trim variants the EPA rates separately, the annual fuel cost across three driving patterns, and a year-over-year comparison so you can see whether the car has improved.
Fuel economy by model year
Combined MPG, city MPG, highway MPG, and the EPA's estimated annual fuel cost for every model year of the Mercedes-Benz E450 4matic (station wagon). Click any year to see the full breakdown for that model year, including trim variants, the drivetrain, and a comparison against other vehicles in its segment.
| Year | Model | Combined MPG | City | Highway | Annual fuel cost |
|---|---|---|---|---|---|
| 2020 | 2020 Mercedes-Benz E450 4matic (station wagon) | 22 MPG | 19 MPG | 26 MPG | $3,150 |
| 2019 | 2019 Mercedes-Benz E450 4matic (station wagon) | 22 MPG | 19 MPG | 26 MPG | $3,150 |
How the Mercedes-Benz E450 4matic (station wagon) compares against the Midsize Station Wagons class
Buyers usually compare the Mercedes-Benz E450 4matic (station wagon) against other cars in the same EPA class. The list below shows the most efficient cars in the Midsize Station Wagons class for the 2020 model year, the latest year on this page. Each link opens the full page for that car.
Source: U.S. EPA fuel economy dataset. Annual fuel cost assumes 15,000 miles of driving per year and a 55% city, 45% highway split.