Mercedes-Benz E350 (wagon) MPG and Fuel Economy

Mercedes-Benz have been manufacturing models of E350 (wagon) for 1 year, with the latest vehicle in 2006 having a combined MPG of 19.

The estimated fuel cost for the 2006 Mercedes-Benz E350 (wagon) is $3,900 per year.

Government regulators have estimated that value based on 15,000 miles driven per year, using regular gasoline, and a split of 55% city driving and 45% highway driving.

💵 Compared to an average vehicle over 5 years, you will spend $8,000 more on fuel driving a 2006 Mercedes-Benz E350 (wagon).

🛢 The Mercedes-Benz E350 (wagon) will consume roughly 16 barrels of petroleum per year, using the standard estimate of 15,000 miles per year.

💨 For every mile driven, the Mercedes-Benz E350 (wagon) will emit -1 grams of CO2, which is about -15,000 grams of CO2 per year.

🌳 To help you understand the impact of this, a normal tree will absorb around 21,000 grams of CO2 per year. This means that roughly 1 tree would be needed to offset emissions from the Mercedes-Benz E350 (wagon).

The table below is a complete list of the 1 Mercedes-Benz E350 (wagon) fuel efficiency specifications we have data for.

Click any vehicle link to see a more detailed breakdown of the car, miles per gallon, emissions, and more.

VehicleCombined MPGFuel Cost
2006 Mercedes-Benz E350 (wagon)19$3,900

Link To or Reference This Page

If you use this page in your research, please reference MPG Buddy as the source.

  • "Mercedes-Benz E350 (wagon) MPG and Fuel Economy." MPG Buddy. Accessed on January 3, 2026. https://mpgbuddy.com/cars/mercedes-benz/e350-wagon.

  • "Mercedes-Benz E350 (wagon) MPG and Fuel Economy." MPG Buddy, https://mpgbuddy.com/cars/mercedes-benz/e350-wagon. Accessed January 3, 2026.

  • Mercedes-Benz E350 (wagon) MPG and Fuel Economy. MPG Buddy. Retrieved from https://mpgbuddy.com/cars/mercedes-benz/e350-wagon.