This page collects every fuel-economy figure the EPA publishes for the 2016 Mercedes-Benz CLS400 4matic. Below you will find the headline combined, city, and highway MPG, the estimated annual fuel cost at three different driving levels, the tailpipe CO₂ emissions, and a full breakdown of the engine and drivetrain. If you want to know whether this generation got more or less efficient over the years, the year-over-year table further down covers every model year the EPA has rated.

Key takeaways

  • Returns 21% worse combined MPG than the average car in the Compact Cars class for the 2016 model year (27.7 MPG class average).
  • The most efficient car in the Compact Cars class for the 2016 model year is the Volkswagen e-Golf at 116 MPG.
  • EPA estimates this car costs around $5,000 more in fuel over five years than an average new vehicle of the same model year.
  • Requires premium gasoline, which typically adds about 40 to 60 cents per gallon to the EPA's annual fuel cost estimate.

Fuel economy at a glance

These are the EPA's official ratings for the 2016 Mercedes-Benz CLS400 4matic. The numbers come from a standardised laboratory test cycle and are the same figures that appear on the window sticker of every new car. Real-world mileage varies with driving style, weather, fuel quality, and how heavily loaded the car is.

Combined MPG is a 55/45 weighted blend of the city and highway test cycles. The EPA uses it as the single number you can compare across the entire dataset, including hybrids and EVs (which use the equivalent MPGe figure).

Combined MPG 22 MPG
City MPG 19 MPG
Highway MPG 26 MPG
Annual fuel cost $3,150
Tailpipe CO₂ 405 g/mi
Fuel type Premium

How the 2016 Mercedes-Benz CLS400 4matic compares

The 2016 Mercedes-Benz CLS400 4matic returns 22 combined MPG. Cars in the Compact Cars class for the same model year average 27.7 MPG, which puts this car behind the class average by about 21%.

The most efficient car in the Compact Cars class for the 2016 model year is the Volkswagen e-Golf at 116 MPG. The bar chart below puts the Mercedes-Benz CLS400 4matic alongside the class best and the class average so you can see the full picture.

For broader context, the average new car of the 2016 model year (across all classes) returns 25.9 MPG. Larger vehicles pull the all-cars average down, so do not use that figure on its own to judge a small car or a hybrid. The full list of the most efficient cars of the 2016 model year is on its own page.

2016 Mercedes-Benz CLS400 4matic
22 MPG
Class average, 2016
27.7 MPG
Class best, 2016
116 MPG
Average new car, 2016
25.9 MPG

Annual fuel cost across driving patterns

The headline annual fuel cost the EPA publishes assumes 15,000 miles of driving per year and a fuel mix of 55% city and 45% highway. The dollar figure is calculated using the EPA's current reference price for premium gasoline, which is $4.61/gallon. EPA updates that reference periodically rather than tracking live pump prices, so treat it as a window-sticker estimate rather than today's pump number.

The table below scales the EPA's number to three common driving patterns. The combined MPG and the reference fuel price stay constant, only the annual mileage changes. To get a current-prices estimate, take your local gas price and multiply by 681.8 gallons (the car's annual consumption at the rated MPG).

Driving pattern Estimated annual fuel cost
Light driver, 7,500 miles per year $1,575
Average driver, 15,000 miles per year $3,150
Heavy driver, 25,000 miles per year $5,250

Year-over-year MPG for the Mercedes-Benz CLS400 4matic

The EPA has rated the Mercedes-Benz CLS400 4matic across 2 model years, from 2015 Mercedes-Benz CLS400 4matic through 2016 Mercedes-Benz CLS400 4matic. The numbers below are the best combined MPG figure the EPA published for each year, which lets you see when the car was at its most efficient and how recent generations stack up.

Combined MPG has stayed in roughly the same range across the run, hovering close to 22 MPG.

Year Combined MPG Open year page
2016 22 MPG this page
2015 22 MPG 2015 Mercedes-Benz CLS400 4matic

Compare against other Compact Cars for 2016

If you are cross-shopping the 2016 Mercedes-Benz CLS400 4matic, the most useful comparison is against the other cars in the Compact Cars class for the same model year. The list below shows the highest-MPG peers, ranked from most to least efficient. Click any of them to open its full page.

The Volkswagen e-Golf leads this group at 116 MPG, 94 MPG ahead of the 2016 Mercedes-Benz CLS400 4matic.

Specifications

The 2016 Mercedes-Benz CLS400 4matic runs a 3-liter 6-cylinder turbocharged engine paired with a automatic 7-spd, sending power through 4-wheel drive.

Engine, transmission, and drivetrain together drive most of the variation in fuel economy across trims. A larger engine moves the car with less effort but burns more fuel. A turbo lets a small engine punch above its weight, often without much MPG penalty. All-wheel drive adds traction and weight, and usually costs a couple of MPG compared with two-wheel drive of the same engine.

Vehicle class
Compact Cars
Engine
3L 6-cylinder turbocharged
Transmission
Automatic 7-spd
Drivetrain
4-Wheel Drive
Fuel type
Premium
Annual petroleum use
13.5 barrels per year
Start-stop system
Yes

Common questions about the 2016 Mercedes-Benz CLS400 4matic

Quick answers to the questions people most often search for when looking up the 2016 Mercedes-Benz CLS400 4matic.

  • Is the 2016 Mercedes-Benz CLS400 4matic fuel efficient?
    Not particularly. The 2016 Mercedes-Benz CLS400 4matic returns 22 combined MPG, which trails the average car in the Compact Cars class for the same model year by about 21%.
  • What MPG does the 2016 Mercedes-Benz CLS400 4matic get?
    The EPA rates the 2016 Mercedes-Benz CLS400 4matic at 22 combined MPG, 19 MPG in city driving, and 26 MPG on the highway. Real-world numbers depend on your driving style, the weather, and how loaded the car is.
  • How much does it cost to fuel a 2016 Mercedes-Benz CLS400 4matic per year?
    The EPA estimates an annual fuel cost of $3,150 for the 2016 Mercedes-Benz CLS400 4matic. That figure assumes 15,000 miles of driving per year, a 55% city and 45% highway split, and the EPA's published average fuel price for the rated fuel grade.
  • Does the 2016 Mercedes-Benz CLS400 4matic require premium gas?
    Yes. The EPA lists the 2016 Mercedes-Benz CLS400 4matic as requiring premium gasoline. Running it on regular can reduce performance and may affect engine warranties, so it is not a recommended way to save at the pump.
  • How much CO₂ does the 2016 Mercedes-Benz CLS400 4matic emit?
    Tailpipe CO₂ emissions are 405 g/mi. Multiplied across a typical year of driving (15,000 miles) that works out to about 6,075 kilograms of CO₂.
  • What is the difference between the city and highway MPG of the 2016 Mercedes-Benz CLS400 4matic?
    City driving returns 19 MPG and highway driving returns 26 MPG, a gap of 7 MPG. A spread that wide is typical of cars with conventional automatic or manual transmissions, where stop-start city traffic eats more fuel than a steady highway cruise.
  • What engine is in the 2016 Mercedes-Benz CLS400 4matic?
    The 2016 Mercedes-Benz CLS400 4matic has a 3-liter 6-cylinder turbocharged engine (EPA description: SIDI).
  • What transmission and drivetrain does the 2016 Mercedes-Benz CLS400 4matic have?
    The 2016 Mercedes-Benz CLS400 4matic comes with a automatic 7-spd transmission and 4-wheel drive.
  • How does the 2016 Mercedes-Benz CLS400 4matic compare to the best car in its class?
    The most efficient car in the Compact Cars class for the 2016 model year is the Volkswagen e-Golf at 116 combined MPG. The Mercedes-Benz CLS400 4matic returns 22 MPG, a gap of 94 MPG. If you are comparing on fuel economy alone, the class leader is worth a look.
  • How much more does the 2016 Mercedes-Benz CLS400 4matic cost in fuel compared to an average car?
    The EPA estimates that over five years, the 2016 Mercedes-Benz CLS400 4matic will cost about $5,000 more in fuel than an average new vehicle of the same model year. The difference accumulates because the car uses more fuel per mile, not because of any one-off charge at the dealership.

Source: U.S. EPA fuel economy dataset. Annual fuel cost figures assume 15,000 miles of driving per year and a 55% city, 45% highway split. Real-world mileage varies with driving conditions, vehicle maintenance, fuel quality, and driver behaviour.