This page collects every fuel-economy figure the EPA publishes for the 2012 Mercedes-Benz C300 4matic. Below you will find the headline combined, city, and highway MPG, the estimated annual fuel cost at three different driving levels, the tailpipe CO₂ emissions, and a full breakdown of the engine and drivetrain. The EPA rates 2 separate variants of this car (different engine, transmission, or drivetrain combinations), and you can compare them side by side in the trims table. If you want to know whether this generation got more or less efficient over the years, the year-over-year table further down covers every model year the EPA has rated.

Key takeaways

  • Returns 24% worse combined MPG than the average car in the Compact Cars class for the 2012 model year (26.3 MPG class average).
  • The most efficient car in the Compact Cars class for the 2012 model year is the Ford Focus Electric at 105 MPG.
  • The Mercedes-Benz C300 4matic has gained 7 MPG since its first rated model year, the 2008 Mercedes-Benz C300 4matic at 20 MPG.
  • EPA estimates this car costs around $6,500 more in fuel over five years than an average new vehicle of the same model year.
  • Requires premium gasoline, which typically adds about 40 to 60 cents per gallon to the EPA's annual fuel cost estimate.

Fuel economy at a glance

These are the EPA's official ratings for the 2012 Mercedes-Benz C300 4matic. The numbers come from a standardised laboratory test cycle and are the same figures that appear on the window sticker of every new car. Real-world mileage varies with driving style, weather, fuel quality, and how heavily loaded the car is.

When the EPA tests several variants of the same nameplate (for example, a front-wheel-drive version and an all-wheel-drive version), each gets its own rating. The figures shown here are the headline variant, taken as the configuration with the best combined MPG. The trims table further down covers all 2 variants side by side.

Combined MPG is a 55/45 weighted blend of the city and highway test cycles. The EPA uses it as the single number you can compare across the entire dataset, including hybrids and EVs (which use the equivalent MPGe figure).

Combined MPG 20 MPG
City MPG 17 MPG
Highway MPG 24 MPG
Annual fuel cost $3,450
Tailpipe CO₂ 444 g/mi
Fuel type Premium

How the 2012 Mercedes-Benz C300 4matic compares

The 2012 Mercedes-Benz C300 4matic returns 20 combined MPG. Cars in the Compact Cars class for the same model year average 26.3 MPG, which puts this car behind the class average by about 24%.

The most efficient car in the Compact Cars class for the 2012 model year is the Ford Focus Electric at 105 MPG. The bar chart below puts the Mercedes-Benz C300 4matic alongside the class best and the class average so you can see the full picture.

For broader context, the average new car of the 2012 model year (across all classes) returns 21.7 MPG. Larger vehicles pull the all-cars average down, so do not use that figure on its own to judge a small car or a hybrid. The full list of the most efficient cars of the 2012 model year is on its own page.

2012 Mercedes-Benz C300 4matic
20 MPG
Class average, 2012
26.3 MPG
Class best, 2012
105 MPG
Average new car, 2012
21.7 MPG

Trim variants rated for 2012

The EPA rates 2 separate variants of the 2012 Mercedes-Benz C300 4matic. The differences come from the engine size, transmission type, and drivetrain (front-wheel drive, all-wheel drive, and so on). The same nameplate can land several MPG apart depending on the configuration you actually buy.

Engine and transmission Drive Combined City Highway Annual cost
3L, 6-cyl, Automatic 7-spd 4-Wheel Drive 20 MPG 17 MPG 24 MPG $3,450
3L, 6-cyl, Automatic 7-spd 4-Wheel Drive 20 MPG 18 MPG 25 MPG $3,450

Annual fuel cost across driving patterns

The headline annual fuel cost the EPA publishes assumes 15,000 miles of driving per year and a fuel mix of 55% city and 45% highway. The dollar figure is calculated using the EPA's current reference price for premium gasoline, which is $4.61/gallon. EPA updates that reference periodically rather than tracking live pump prices, so treat it as a window-sticker estimate rather than today's pump number.

The table below scales the EPA's number to three common driving patterns. The combined MPG and the reference fuel price stay constant, only the annual mileage changes. To get a current-prices estimate, take your local gas price and multiply by 750 gallons (the car's annual consumption at the rated MPG).

Driving pattern Estimated annual fuel cost
Light driver, 7,500 miles per year $1,725
Average driver, 15,000 miles per year $3,450
Heavy driver, 25,000 miles per year $5,750

Year-over-year MPG for the Mercedes-Benz C300 4matic

The EPA has rated the Mercedes-Benz C300 4matic across 19 model years, from 2008 Mercedes-Benz C300 4matic through 2026 Mercedes-Benz C300 4matic. The numbers below are the best combined MPG figure the EPA published for each year, which lets you see when the car was at its most efficient and how recent generations stack up.

The 2008 Mercedes-Benz C300 4matic returned 20 MPG. The most recent 2026 Mercedes-Benz C300 4matic returns 27 MPG. That is an improvement of 7 MPG over 18 model years, the kind of gain that usually comes from smaller engines, hybrid systems, or aerodynamic redesigns.

Year Combined MPG Open year page
2026 27 MPG 2026 Mercedes-Benz C300 4matic
2025 27 MPG 2025 Mercedes-Benz C300 4matic
2024 27 MPG 2024 Mercedes-Benz C300 4matic
2023 27 MPG 2023 Mercedes-Benz C300 4matic
2022 27 MPG 2022 Mercedes-Benz C300 4matic
2021 27 MPG 2021 Mercedes-Benz C300 4matic
2020 26 MPG 2020 Mercedes-Benz C300 4matic
2019 26 MPG 2019 Mercedes-Benz C300 4matic
2018 26 MPG 2018 Mercedes-Benz C300 4matic
2017 27 MPG 2017 Mercedes-Benz C300 4matic
2016 27 MPG 2016 Mercedes-Benz C300 4matic
2015 27 MPG 2015 Mercedes-Benz C300 4matic
2014 22 MPG 2014 Mercedes-Benz C300 4matic
2013 22 MPG 2013 Mercedes-Benz C300 4matic
2012 20 MPG this page
2011 20 MPG 2011 Mercedes-Benz C300 4matic
2010 20 MPG 2010 Mercedes-Benz C300 4matic
2009 20 MPG 2009 Mercedes-Benz C300 4matic
2008 20 MPG 2008 Mercedes-Benz C300 4matic

Compare against other Compact Cars for 2012

If you are cross-shopping the 2012 Mercedes-Benz C300 4matic, the most useful comparison is against the other cars in the Compact Cars class for the same model year. The list below shows the highest-MPG peers, ranked from most to least efficient. Click any of them to open its full page.

The Ford Focus Electric leads this group at 105 MPG, 85 MPG ahead of the 2012 Mercedes-Benz C300 4matic.

Specifications

The 2012 Mercedes-Benz C300 4matic runs a 3-liter 6-cylinder engine paired with a automatic 7-spd, sending power through 4-wheel drive.

Engine, transmission, and drivetrain together drive most of the variation in fuel economy across trims. A larger engine moves the car with less effort but burns more fuel. A turbo lets a small engine punch above its weight, often without much MPG penalty. All-wheel drive adds traction and weight, and usually costs a couple of MPG compared with two-wheel drive of the same engine.

Vehicle class
Compact Cars
Engine
3L 6-cylinder
Transmission
Automatic 7-spd
Drivetrain
4-Wheel Drive
Fuel type
Premium
Annual petroleum use
14.9 barrels per year

Common questions about the 2012 Mercedes-Benz C300 4matic

Quick answers to the questions people most often search for when looking up the 2012 Mercedes-Benz C300 4matic.

  • Is the 2012 Mercedes-Benz C300 4matic fuel efficient?
    Not particularly. The 2012 Mercedes-Benz C300 4matic returns 20 combined MPG, which trails the average car in the Compact Cars class for the same model year by about 24%.
  • What MPG does the 2012 Mercedes-Benz C300 4matic get?
    The EPA rates the 2012 Mercedes-Benz C300 4matic at 20 combined MPG, 17 MPG in city driving, and 24 MPG on the highway. Real-world numbers depend on your driving style, the weather, and how loaded the car is.
  • How much does it cost to fuel a 2012 Mercedes-Benz C300 4matic per year?
    The EPA estimates an annual fuel cost of $3,450 for the 2012 Mercedes-Benz C300 4matic. That figure assumes 15,000 miles of driving per year, a 55% city and 45% highway split, and the EPA's published average fuel price for the rated fuel grade.
  • Does the 2012 Mercedes-Benz C300 4matic require premium gas?
    Yes. The EPA lists the 2012 Mercedes-Benz C300 4matic as requiring premium gasoline. Running it on regular can reduce performance and may affect engine warranties, so it is not a recommended way to save at the pump.
  • Has the Mercedes-Benz C300 4matic become more fuel efficient over time?
    Yes. The first EPA-rated Mercedes-Benz C300 4matic, the 2008 Mercedes-Benz C300 4matic, returned 20 combined MPG. The most recent 2026 Mercedes-Benz C300 4matic returns 27 MPG, an improvement of 7 MPG over the run.
  • How much CO₂ does the 2012 Mercedes-Benz C300 4matic emit?
    Tailpipe CO₂ emissions are 444 g/mi. Multiplied across a typical year of driving (15,000 miles) that works out to about 6,665 kilograms of CO₂.
  • What is the difference between the city and highway MPG of the 2012 Mercedes-Benz C300 4matic?
    City driving returns 17 MPG and highway driving returns 24 MPG, a gap of 7 MPG. A spread that wide is typical of cars with conventional automatic or manual transmissions, where stop-start city traffic eats more fuel than a steady highway cruise.
  • What engine is in the 2012 Mercedes-Benz C300 4matic?
    The 2012 Mercedes-Benz C300 4matic has a 3-liter 6-cylinder engine.
  • What transmission and drivetrain does the 2012 Mercedes-Benz C300 4matic have?
    The 2012 Mercedes-Benz C300 4matic comes with a automatic 7-spd transmission and 4-wheel drive.
  • How does the 2012 Mercedes-Benz C300 4matic compare to the best car in its class?
    The most efficient car in the Compact Cars class for the 2012 model year is the Ford Focus Electric at 105 combined MPG. The Mercedes-Benz C300 4matic returns 20 MPG, a gap of 85 MPG. If you are comparing on fuel economy alone, the class leader is worth a look.

Source: U.S. EPA fuel economy dataset. Annual fuel cost figures assume 15,000 miles of driving per year and a 55% city, 45% highway split. Real-world mileage varies with driving conditions, vehicle maintenance, fuel quality, and driver behaviour.