Mercedes-Benz AMG GLS63 4matic Plus: MPG and fuel economy by year

The EPA has rated the Mercedes-Benz AMG GLS63 4matic Plus across 6 model years, from the 2021 Mercedes-Benz AMG GLS63 4matic Plus through the 2026 Mercedes-Benz AMG GLS63 4matic Plus. The most recent 2026 Mercedes-Benz AMG GLS63 4matic Plus returns 17 combined MPG.

Pick a year below to open the full Mercedes-Benz AMG GLS63 4matic Plus page for that model year. Each year page covers combined, city, and highway MPG, the trim variants the EPA rates separately, the annual fuel cost across three driving patterns, and a year-over-year comparison so you can see whether the car has improved.

Fuel economy by model year

Combined MPG, city MPG, highway MPG, and the EPA's estimated annual fuel cost for every model year of the Mercedes-Benz AMG GLS63 4matic Plus. Click any year to see the full breakdown for that model year, including trim variants, the drivetrain, and a comparison against other vehicles in its segment.

Year	Model	Combined MPG	City	Highway	Annual fuel cost
2026	2026 Mercedes-Benz AMG GLS63 4matic Plus	17 MPG	15 MPG	20 MPG	$4,050
2025	2025 Mercedes-Benz AMG GLS63 4matic Plus	15 MPG	14 MPG	18 MPG	$4,600
2024	2024 Mercedes-Benz AMG GLS63 4matic Plus	16 MPG	14 MPG	18 MPG	$4,300
2023	2023 Mercedes-Benz AMG GLS63 4matic Plus	16 MPG	14 MPG	19 MPG	$4,300
2022	2022 Mercedes-Benz AMG GLS63 4matic Plus	15 MPG	14 MPG	18 MPG	$4,600
2021	2021 Mercedes-Benz AMG GLS63 4matic Plus	16 MPG	14 MPG	18 MPG	$4,300

How the Mercedes-Benz AMG GLS63 4matic Plus compares against the Standard Sport Utility Vehicle 4WD class

Buyers usually compare the Mercedes-Benz AMG GLS63 4matic Plus against other cars in the same EPA class. The list below shows the most efficient cars in the Standard Sport Utility Vehicle 4WD class for the 2026 model year, the latest year on this page. Each link opens the full page for that car.

Source: U.S. EPA fuel economy dataset. Annual fuel cost assumes 15,000 miles of driving per year and a 55% city, 45% highway split.