Pick a year below to open the full Mercedes-Benz AMG GLE63 S 4matic Plus page for that model year. Each year page covers combined, city, and highway MPG, the trim variants the EPA rates separately, the annual fuel cost across three driving patterns, and a year-over-year comparison so you can see whether the car has improved.

Fuel economy by model year

Combined MPG, city MPG, highway MPG, and the EPA's estimated annual fuel cost for every model year of the Mercedes-Benz AMG GLE63 S 4matic Plus. Click any year to see the full breakdown for that model year, including trim variants, the drivetrain, and a comparison against other vehicles in its segment.

Year Model Combined MPG City Highway Annual fuel cost
2026 2026 Mercedes-Benz AMG GLE63 S 4matic Plus 17 MPG 15 MPG 20 MPG $4,050
2025 2025 Mercedes-Benz AMG GLE63 S 4matic Plus 16 MPG 14 MPG 19 MPG $4,300
2024 2024 Mercedes-Benz AMG GLE63 S 4matic Plus 16 MPG 15 MPG 19 MPG $4,300
2023 2023 Mercedes-Benz AMG GLE63 S 4matic Plus 17 MPG 15 MPG 20 MPG $4,050
2022 2022 Mercedes-Benz AMG GLE63 S 4matic Plus 16 MPG 15 MPG 19 MPG $4,300
2021 2021 Mercedes-Benz AMG GLE63 S 4matic Plus 16 MPG 15 MPG 19 MPG $4,300

How the Mercedes-Benz AMG GLE63 S 4matic Plus compares against the Standard Sport Utility Vehicle 4WD class

Buyers usually compare the Mercedes-Benz AMG GLE63 S 4matic Plus against other cars in the same EPA class. The list below shows the most efficient cars in the Standard Sport Utility Vehicle 4WD class for the 2026 model year, the latest year on this page. Each link opens the full page for that car.

Source: U.S. EPA fuel economy dataset. Annual fuel cost assumes 15,000 miles of driving per year and a 55% city, 45% highway split.