2021 Mercedes-Benz AMG E63 S 4matic Plus MPG and Fuel Economy

On this page, you will find a complete guide to the miles per gallon and fuel efficiency data for the 2021 Mercedes-Benz AMG E63 S 4matic Plus.

The 2021 Mercedes-Benz AMG E63 S 4matic Plus runs on premium gasoline and is in the Midsize Cars car class.

Whether you are considering a purchase of the car, or just wanting to find out how economical and environmentally friendly (or un-friendly) your 2021 Mercedes-Benz AMG E63 S 4matic Plus is, we have the information you need.

🛣 How Many Miles per Gallon (MPG) Does a 2021 Mercedes-Benz AMG E63 S 4matic Plus Get?

First off, the most commonly asked question. A 2021 Mercedes-Benz AMG E63 S 4matic Plus gets up to 16 miles per gallon in the city, and 23 miles per gallon on the highway.

The combined average MPG for the 2021 Mercedes-Benz AMG E63 S 4matic Plus is 18 miles per gallon.

💵 What is the Average Yearly Fuel Cost for a 2021 Mercedes-Benz AMG E63 S 4matic Plus?

The estimated fuel costs for the 2021 Mercedes-Benz AMG E63 S 4matic Plus is $4,100 per year.

That value has been estimated by government regulators based on 15,000 miles driven per year, using regular gasoline, and a split of 55% city driving and 45% highway driving.

If you were to compare a 2021 Mercedes-Benz AMG E63 S 4matic Plus to an average vehicle over 5 years, you will spend $9,000 more on fuel.

🛢 How Many Barrels of Petroleum Does a 2021 Mercedes-Benz AMG E63 S 4matic Plus Consume?

The 2021 Mercedes-Benz AMG E63 S 4matic Plus will consume roughly 17 barrels of petroleum per year, using the standard estimate of 15,000 miles per year.

The majority of the world's petroleum is sourced from countries like Saudi Arabia, Russia, Iraq, and the United States.

💨 How Many Grams of CO2 Does a 2021 Mercedes-Benz AMG E63 S 4matic Plus Emit?

For every mile driven, the 2021 Mercedes-Benz AMG E63 S 4matic Plus will emit 484 grams of CO2, which is about 7,260,000 grams of CO2 per year.

🌳 To help you understand the impact of this, a normal tree will absorb around 21,000 grams of CO2 per year. This means that roughly 248 trees would be needed to offset emissions from the 2021 Mercedes-Benz AMG E63 S 4matic Plus.

Overview

The table below covers all of the miles per gallon, engine specifications, and emission details we have for the 2021 Mercedes-Benz AMG E63 S 4matic Plus.

City MPG16
Highway MPG23
Combined MPG18
Save/Spend vs Average CarSpend $9,000
Fuel Cost$4,100
Fuel Type 1Premium
Barrels of Petroleum17
Grams of CO27,260,000
Trees Needed to Offset346
Drive4-Wheel Drive
Cylinders8
Displacement4
TransmissionAutomatic 9-spd
Vehicle ClassMidsize Cars
Start/Stop?Yes
Supercharged?No
Turbocharged?Yes

Related Mercedes-Benz Models from 2021

If you're interested in other Mercedes-Benz models from 2021, you can find them in the table below. You can click the model link to find miles per gallon and emission information for that model.

Link To or Reference This Page

If you use this page in your research, please reference MPG Buddy as the source.

  • "2021 Mercedes-Benz AMG E63 S 4matic Plus MPG and Fuel Economy." MPG Buddy. Accessed on January 3, 2026. https://mpgbuddy.com/cars/mercedes-benz/amg-e63-s-4matic-plus/2021.

  • "2021 Mercedes-Benz AMG E63 S 4matic Plus MPG and Fuel Economy." MPG Buddy, https://mpgbuddy.com/cars/mercedes-benz/amg-e63-s-4matic-plus/2021. Accessed January 3, 2026.

  • 2021 Mercedes-Benz AMG E63 S 4matic Plus MPG and Fuel Economy. MPG Buddy. Retrieved from https://mpgbuddy.com/cars/mercedes-benz/amg-e63-s-4matic-plus/2021.