Pick a year below to open the full Mercedes-Benz 420SE page for that model year. Each year page covers combined, city, and highway MPG, the trim variants the EPA rates separately, the annual fuel cost across three driving patterns, and a year-over-year comparison so you can see whether the car has improved.

Fuel economy by model year

Combined MPG, city MPG, highway MPG, and the EPA's estimated annual fuel cost for every model year of the Mercedes-Benz 420SE. Click any year to see the full breakdown for that model year, including trim variants, the drivetrain, and a comparison against other vehicles in its segment.

Year Model Combined MPG City Highway Annual fuel cost
1990 1990 Mercedes-Benz 420SE 13 MPG 12 MPG 15 MPG $5,300

How the Mercedes-Benz 420SE compares against the Midsize Cars class

Buyers usually compare the Mercedes-Benz 420SE against other cars in the same EPA class. The list below shows the most efficient cars in the Midsize Cars class for the 1990 model year, the latest year on this page. Each link opens the full page for that car.

Source: U.S. EPA fuel economy dataset. Annual fuel cost assumes 15,000 miles of driving per year and a 55% city, 45% highway split.