2021 GMC Sierra 2WD MPG and Fuel Economy

On this page, you will find a complete guide to the miles per gallon and fuel efficiency data for the 2021 GMC Sierra 2WD.

The 2021 GMC Sierra 2WD has 9 model options: Automatic 6-spd 8-cyl, 5.3 L, Automatic 6-spd 8-cyl, 5.3 L, Automatic 8-spd 8-cyl, 5.3 L, Automatic 10-spd 6-cyl, 3.0 L, Automatic 6-spd 6-cyl, 4.3 L, Automatic 8-spd 4-cyl, 2.7 L, Automatic 8-spd 4-cyl, 2.7 L, Automatic 6-spd 8-cyl, 5.3 L and Automatic 8-spd 8-cyl, 5.3 L.

The 2021 GMC Sierra 2WD Automatic 6-spd 8-cyl, 5.3 L runs on regular gasoline and is in the Standard Pickup Trucks 2WD car class.

The 2021 GMC Sierra 2WD Automatic 6-spd 8-cyl, 5.3 L runs on regular gasoline and is in the Standard Pickup Trucks 2WD car class.

The 2021 GMC Sierra 2WD Automatic 8-spd 8-cyl, 5.3 L runs on regular gasoline and is in the Standard Pickup Trucks 2WD car class.

The 2021 GMC Sierra 2WD Automatic 10-spd 6-cyl, 3.0 L runs on diesel and is in the Standard Pickup Trucks 2WD car class.

The 2021 GMC Sierra 2WD Automatic 6-spd 6-cyl, 4.3 L runs on regular gasoline and is in the Standard Pickup Trucks 2WD car class.

The 2021 GMC Sierra 2WD Automatic 8-spd 4-cyl, 2.7 L runs on regular gasoline and is in the Standard Pickup Trucks 2WD car class.

The 2021 GMC Sierra 2WD Automatic 8-spd 4-cyl, 2.7 L runs on regular gasoline and is in the Standard Pickup Trucks 2WD car class.

The 2021 GMC Sierra 2WD Automatic 6-spd 8-cyl, 5.3 L runs on regular gasoline and is in the Standard Pickup Trucks 2WD car class.

The 2021 GMC Sierra 2WD Automatic 8-spd 8-cyl, 5.3 L runs on regular gasoline and is in the Standard Pickup Trucks 2WD car class.

🛣 How Many Miles per Gallon (MPG) Does a 2021 GMC Sierra 2WD Get?

Across all models, the combined average MPG for the 2021 GMC Sierra 2WD is 19 miles per gallon.

The table below breaks down the MPG for each model option:

Model OptionCombined MPGCity MPGHighway MPG
Automatic 6-spd 8-cyl, 5.3 L171521
Automatic 6-spd 8-cyl, 5.3 L161519
Automatic 8-spd 8-cyl, 5.3 L191723
Automatic 10-spd 6-cyl, 3.0 L262330
Automatic 6-spd 6-cyl, 4.3 L171621
Automatic 8-spd 4-cyl, 2.7 L212023
Automatic 8-spd 4-cyl, 2.7 L212023
Automatic 6-spd 8-cyl, 5.3 L161421
Automatic 8-spd 8-cyl, 5.3 L171522

💵 What is the Average Yearly Fuel Cost for a 2021 GMC Sierra 2WD?

The average fuel costs for all models of the 2021 GMC Sierra 2WD is $3,461.

The average fuel costs have been estimated by government regulators based on 15,000 miles driven per year, using regular gasoline, and a split of 55% city driving and 45% highway driving.

Comparing a 2021 GMC Sierra 2WD to an average vehicle over 5 years, you will spend $5,806 more on fuel.

The table below shows the fuel costs and 5-year save/spend for each model option:

Model OptionFuel Cost5-Year Save/Spend
Automatic 6-spd 8-cyl, 5.3 L$3,700spend $7,000 more
Automatic 6-spd 8-cyl, 5.3 L$3,900spend $8,000 more
Automatic 8-spd 8-cyl, 5.3 L$3,300spend $5,000 more
Automatic 10-spd 6-cyl, 3.0 L$2,950spend $3,250 more
Automatic 6-spd 6-cyl, 4.3 L$3,700spend $7,000 more
Automatic 8-spd 4-cyl, 2.7 L$3,000spend $3,500 more
Automatic 8-spd 4-cyl, 2.7 L$3,000spend $3,500 more
Automatic 6-spd 8-cyl, 5.3 L$3,900spend $8,000 more
Automatic 8-spd 8-cyl, 5.3 L$3,700spend $7,000 more

🛢 How Many Barrels of Petroleum Does a 2021 GMC Sierra 2WD Consume?

Across all models, the average number barrels of petroleum that the 2021 GMC Sierra 2WD will consume in one year is 17 barrels.

The majority of the world's petroleum is sourced from countries like Saudi Arabia, Russia, Iraq, and the United States.

Model OptionBarrels
Automatic 6-spd 8-cyl, 5.3 L18
Automatic 6-spd 8-cyl, 5.3 L19
Automatic 8-spd 8-cyl, 5.3 L16
Automatic 10-spd 6-cyl, 3.0 L14
Automatic 6-spd 6-cyl, 4.3 L18
Automatic 8-spd 4-cyl, 2.7 L14
Automatic 8-spd 4-cyl, 2.7 L14
Automatic 6-spd 8-cyl, 5.3 L19
Automatic 8-spd 8-cyl, 5.3 L18

💨 How Many Grams of CO2 Does a 2021 GMC Sierra 2WD Emit?

The 2021 GMC Sierra 2WD will emit an average of about 7,250,000 grams of CO2 per year.

🌳 To help you understand the impact of this, a normal tree will absorb around 21,000 grams of CO2 per year. This means that roughly 247 trees would be needed to offset emissions from the 2021 GMC Sierra 2WD.

Overview

The tables below cover all of the miles per gallon, engine specifications, and emission details we have for the 9 2021 GMC Sierra 2WD model options.

Automatic 6-spd 8-cyl, 5.3 L

The table below contains all of the details we have for the 2021 GMC Sierra 2WD Automatic 6-spd 8-cyl, 5.3 L:

City MPG15
Highway MPG21
Combined MPG17
Save/Spend vs Average CarSpend $7,000
Fuel Cost$3,700
Fuel Type 1Regular
Barrels of Petroleum18
Grams of CO27,845,000
Trees Needed to Offset374
DriveRear-Wheel Drive
Cylinders8
Displacement5.3
TransmissionAutomatic 6-spd
Vehicle ClassStandard Pickup Trucks 2WD
Start/Stop?No
Supercharged?No
Turbocharged?No

Automatic 6-spd 8-cyl, 5.3 L

The table below contains all of the details we have for the 2021 GMC Sierra 2WD Automatic 6-spd 8-cyl, 5.3 L:

City MPG15
Highway MPG19
Combined MPG16
Save/Spend vs Average CarSpend $8,000
Fuel Cost$3,900
Fuel Type 1Gasoline or E85
Fuel Type 2E85
ATV TypeFFV
Barrels of Petroleum19
Grams of CO28,205,000
Trees Needed to Offset391
DriveRear-Wheel Drive
Cylinders8
Displacement5.3
TransmissionAutomatic 6-spd
Vehicle ClassStandard Pickup Trucks 2WD
Start/Stop?No
Supercharged?No
Turbocharged?No

Automatic 8-spd 8-cyl, 5.3 L

The table below contains all of the details we have for the 2021 GMC Sierra 2WD Automatic 8-spd 8-cyl, 5.3 L:

City MPG17
Highway MPG23
Combined MPG19
Save/Spend vs Average CarSpend $5,000
Fuel Cost$3,300
Fuel Type 1Regular
Barrels of Petroleum16
Grams of CO26,990,000
Trees Needed to Offset333
DriveRear-Wheel Drive
Cylinders8
Displacement5.3
TransmissionAutomatic 8-spd
Vehicle ClassStandard Pickup Trucks 2WD
Start/Stop?Yes
Supercharged?No
Turbocharged?No

Automatic 10-spd 6-cyl, 3.0 L

The table below contains all of the details we have for the 2021 GMC Sierra 2WD Automatic 10-spd 6-cyl, 3.0 L:

City MPG23
Highway MPG30
Combined MPG26
Save/Spend vs Average CarSpend $3,250
Fuel Cost$2,950
Fuel Type 1Diesel
ATV TypeDiesel
Barrels of Petroleum14
Grams of CO25,880,000
Trees Needed to Offset280
DriveRear-Wheel Drive
Cylinders6
Displacement3
TransmissionAutomatic 10-spd
Vehicle ClassStandard Pickup Trucks 2WD
Start/Stop?Yes
Supercharged?No
Turbocharged?Yes

Automatic 6-spd 6-cyl, 4.3 L

The table below contains all of the details we have for the 2021 GMC Sierra 2WD Automatic 6-spd 6-cyl, 4.3 L:

City MPG16
Highway MPG21
Combined MPG17
Save/Spend vs Average CarSpend $7,000
Fuel Cost$3,700
Fuel Type 1Regular
Barrels of Petroleum18
Grams of CO27,845,000
Trees Needed to Offset374
DriveRear-Wheel Drive
Cylinders6
Displacement4.3
TransmissionAutomatic 6-spd
Vehicle ClassStandard Pickup Trucks 2WD
Start/Stop?No
Supercharged?No
Turbocharged?No

Automatic 8-spd 4-cyl, 2.7 L

The table below contains all of the details we have for the 2021 GMC Sierra 2WD Automatic 8-spd 4-cyl, 2.7 L:

City MPG20
Highway MPG23
Combined MPG21
Save/Spend vs Average CarSpend $3,500
Fuel Cost$3,000
Fuel Type 1Regular
Barrels of Petroleum14
Grams of CO26,315,000
Trees Needed to Offset301
DriveRear-Wheel Drive
Cylinders4
Displacement2.7
TransmissionAutomatic 8-spd
Vehicle ClassStandard Pickup Trucks 2WD
Start/Stop?Yes
Supercharged?No
Turbocharged?Yes

Automatic 8-spd 4-cyl, 2.7 L

The table below contains all of the details we have for the 2021 GMC Sierra 2WD Automatic 8-spd 4-cyl, 2.7 L:

City MPG20
Highway MPG23
Combined MPG21
Save/Spend vs Average CarSpend $3,500
Fuel Cost$3,000
Fuel Type 1Regular
Barrels of Petroleum14
Grams of CO26,330,000
Trees Needed to Offset301
DriveRear-Wheel Drive
Cylinders4
Displacement2.7
TransmissionAutomatic 8-spd
Vehicle ClassStandard Pickup Trucks 2WD
Start/Stop?Yes
Supercharged?No
Turbocharged?Yes

Automatic 6-spd 8-cyl, 5.3 L

The table below contains all of the details we have for the 2021 GMC Sierra 2WD Automatic 6-spd 8-cyl, 5.3 L:

City MPG14
Highway MPG21
Combined MPG16
Save/Spend vs Average CarSpend $8,000
Fuel Cost$3,900
Fuel Type 1Regular
Barrels of Petroleum19
Grams of CO28,115,000
Trees Needed to Offset386
DriveRear-Wheel Drive
Cylinders8
Displacement5.3
TransmissionAutomatic 6-spd
Vehicle ClassStandard Pickup Trucks 2WD
Start/Stop?No
Supercharged?No
Turbocharged?No

Automatic 8-spd 8-cyl, 5.3 L

The table below contains all of the details we have for the 2021 GMC Sierra 2WD Automatic 8-spd 8-cyl, 5.3 L:

City MPG15
Highway MPG22
Combined MPG17
Save/Spend vs Average CarSpend $7,000
Fuel Cost$3,700
Fuel Type 1Regular
Barrels of Petroleum18
Grams of CO27,725,000
Trees Needed to Offset368
DriveRear-Wheel Drive
Cylinders8
Displacement5.3
TransmissionAutomatic 8-spd
Vehicle ClassStandard Pickup Trucks 2WD
Start/Stop?Yes
Supercharged?No
Turbocharged?No

Link To or Reference This Page

If you use this page in your research, please reference MPG Buddy as the source.

  • "2021 GMC Sierra 2WD MPG and Fuel Economy." MPG Buddy. Accessed on January 3, 2026. https://mpgbuddy.com/cars/gmc/sierra-2wd/2021.

  • "2021 GMC Sierra 2WD MPG and Fuel Economy." MPG Buddy, https://mpgbuddy.com/cars/gmc/sierra-2wd/2021. Accessed January 3, 2026.

  • 2021 GMC Sierra 2WD MPG and Fuel Economy. MPG Buddy. Retrieved from https://mpgbuddy.com/cars/gmc/sierra-2wd/2021.