Pick a year below to open the full Ford F250 Pickup 4WD page for that model year. Each year page covers combined, city, and highway MPG, the trim variants the EPA rates separately, the annual fuel cost across three driving patterns, and a year-over-year comparison so you can see whether the car has improved.

Fuel economy by model year

Combined MPG, city MPG, highway MPG, and the EPA's estimated annual fuel cost for every model year of the Ford F250 Pickup 4WD. Click any year to see the full breakdown for that model year, including trim variants, the drivetrain, and a comparison against other vehicles in its segment.

Year Model Combined MPG City Highway Annual fuel cost
1999 1999 Ford F250 Pickup 4WD 13 MPG 12 MPG 15 MPG $4,600
1998 1998 Ford F250 Pickup 4WD 14 MPG 12 MPG 16 MPG $4,300
1997 1997 Ford F250 Pickup 4WD 14 MPG 12 MPG 17 MPG $4,300
1991 1991 Ford F250 Pickup 4WD 14 MPG 13 MPG 17 MPG $4,300
1990 1990 Ford F250 Pickup 4WD 14 MPG 13 MPG 16 MPG $4,300
1989 1989 Ford F250 Pickup 4WD 14 MPG 13 MPG 16 MPG $4,300
1988 1988 Ford F250 Pickup 4WD 15 MPG 14 MPG 17 MPG $4,000
1987 1987 Ford F250 Pickup 4WD 14 MPG 13 MPG 15 MPG $4,300
1986 1986 Ford F250 Pickup 4WD 15 MPG 14 MPG 16 MPG $4,000
1985 1985 Ford F250 Pickup 4WD 16 MPG 15 MPG 17 MPG $3,750
1984 1984 Ford F250 Pickup 4WD 14 MPG 13 MPG 15 MPG $4,300

How the Ford F250 Pickup 4WD compares against the Standard Pickup Trucks 4WD class

Buyers usually compare the Ford F250 Pickup 4WD against other cars in the same EPA class. The list below shows the most efficient cars in the Standard Pickup Trucks 4WD class for the 1999 model year, the latest year on this page. Each link opens the full page for that car.

Source: U.S. EPA fuel economy dataset. Annual fuel cost assumes 15,000 miles of driving per year and a 55% city, 45% highway split.