This page collects every fuel-economy figure the EPA publishes for the 2021 Ford F150 Pickup 4WD HEV. Below you will find the headline combined, city, and highway MPG, the estimated annual fuel cost at three different driving levels, the tailpipe CO₂ emissions, and a full breakdown of the engine and drivetrain. If you want to know whether this generation got more or less efficient over the years, the year-over-year table further down covers every model year the EPA has rated.

Key takeaways

  • Returns 28% better combined MPG than the average car in the Standard Pickup Trucks 4WD class for the 2021 model year (18.7 MPG class average).
  • The 2021 Ford F150 Pickup 4WD HEV is the most efficient car in the Standard Pickup Trucks 4WD class for the 2021 model year, with its 24 MPG rating leading the segment.
  • EPA estimates this car costs around $1,750 more in fuel over five years than an average new vehicle of the same model year.

Fuel economy at a glance

These are the EPA's official ratings for the 2021 Ford F150 Pickup 4WD HEV. The numbers come from a standardised laboratory test cycle and are the same figures that appear on the window sticker of every new car. Real-world mileage varies with driving style, weather, fuel quality, and how heavily loaded the car is.

Combined MPG is a 55/45 weighted blend of the city and highway test cycles. The EPA uses it as the single number you can compare across the entire dataset, including hybrids and EVs (which use the equivalent MPGe figure).

Combined MPG 24 MPG
City MPG 24 MPG
Highway MPG 24 MPG
Annual fuel cost $2,500
Tailpipe CO₂ 368 g/mi
Fuel type Regular

How the 2021 Ford F150 Pickup 4WD HEV compares

The 2021 Ford F150 Pickup 4WD HEV returns 24 combined MPG. Cars in the Standard Pickup Trucks 4WD class for the same model year average 18.7 MPG, which puts this car ahead of the class average by about 28%.

Within the Standard Pickup Trucks 4WD class for the 2021 model year, the Ford F150 Pickup 4WD HEV is the leader. No other car in the same class beat its 24 MPG rating. The bar chart below shows it alongside the class average and the average new car for some additional context.

For broader context, the average new car of the 2021 model year (across all classes) returns 27.9 MPG. Larger vehicles pull the all-cars average down, so do not use that figure on its own to judge a small car or a hybrid. The full list of the most efficient cars of the 2021 model year is on its own page.

2021 Ford F150 Pickup 4WD HEV
24 MPG
Class average, 2021
18.7 MPG
Average new car, 2021
27.9 MPG

Annual fuel cost across driving patterns

The headline annual fuel cost the EPA publishes assumes 15,000 miles of driving per year and a fuel mix of 55% city and 45% highway. The dollar figure is calculated using the EPA's current reference price for regular gasoline, which is $3.99/gallon. EPA updates that reference periodically rather than tracking live pump prices, so treat it as a window-sticker estimate rather than today's pump number.

The table below scales the EPA's number to three common driving patterns. The combined MPG and the reference fuel price stay constant, only the annual mileage changes. To get a current-prices estimate, take your local gas price and multiply by 625 gallons (the car's annual consumption at the rated MPG).

Driving pattern Estimated annual fuel cost
Light driver, 7,500 miles per year $1,250
Average driver, 15,000 miles per year $2,500
Heavy driver, 25,000 miles per year $4,167

Year-over-year MPG for the Ford F150 Pickup 4WD HEV

The EPA has rated the Ford F150 Pickup 4WD HEV across 6 model years, from 2021 Ford F150 Pickup 4WD HEV through 2026 Ford F150 Pickup 4WD HEV. The numbers below are the best combined MPG figure the EPA published for each year, which lets you see when the car was at its most efficient and how recent generations stack up.

Combined MPG has stayed in roughly the same range across the run, hovering close to 23 MPG.

Year Combined MPG Open year page
2026 23 MPG 2026 Ford F150 Pickup 4WD HEV
2025 23 MPG 2025 Ford F150 Pickup 4WD HEV
2024 23 MPG 2024 Ford F150 Pickup 4WD HEV
2023 23 MPG 2023 Ford F150 Pickup 4WD HEV
2022 23 MPG 2022 Ford F150 Pickup 4WD HEV
2021 24 MPG this page

Compare against other Standard Pickup Trucks 4WD for 2021

If you are cross-shopping the 2021 Ford F150 Pickup 4WD HEV, the most useful comparison is against the other cars in the Standard Pickup Trucks 4WD class for the same model year. The list below shows the highest-MPG peers, ranked from most to least efficient. Click any of them to open its full page.

Specifications

The 2021 Ford F150 Pickup 4WD HEV runs a 3.5-liter 6-cylinder turbocharged engine paired with a automatic (s10), sending power through part-time 4-wheel drive.

Engine, transmission, and drivetrain together drive most of the variation in fuel economy across trims. A larger engine moves the car with less effort but burns more fuel. A turbo lets a small engine punch above its weight, often without much MPG penalty. All-wheel drive adds traction and weight, and usually costs a couple of MPG compared with two-wheel drive of the same engine.

Vehicle class
Standard Pickup Trucks 4WD
Engine
3.5L 6-cylinder turbocharged
Transmission
Automatic (S10)
Drivetrain
Part-time 4-Wheel Drive
Fuel type
Regular
Annual petroleum use
12.4 barrels per year
Start-stop system
Yes

Common questions about the 2021 Ford F150 Pickup 4WD HEV

Quick answers to the questions people most often search for when looking up the 2021 Ford F150 Pickup 4WD HEV.

  • Is the 2021 Ford F150 Pickup 4WD HEV fuel efficient?
    Yes. The 2021 Ford F150 Pickup 4WD HEV returns 24 combined MPG, which beats the average car in the Standard Pickup Trucks 4WD class for the same model year by about 28%.
  • What MPG does the 2021 Ford F150 Pickup 4WD HEV get?
    The EPA rates the 2021 Ford F150 Pickup 4WD HEV at 24 combined MPG, 24 MPG in city driving, and 24 MPG on the highway. Real-world numbers depend on your driving style, the weather, and how loaded the car is.
  • How much does it cost to fuel a 2021 Ford F150 Pickup 4WD HEV per year?
    The EPA estimates an annual fuel cost of $2,500 for the 2021 Ford F150 Pickup 4WD HEV. That figure assumes 15,000 miles of driving per year, a 55% city and 45% highway split, and the EPA's published average fuel price for the rated fuel grade.
  • What fuel does the 2021 Ford F150 Pickup 4WD HEV use?
    The EPA lists the 2021 Ford F150 Pickup 4WD HEV as running on regular gasoline. Using a different grade than the manufacturer specifies can affect fuel economy and engine longevity.
  • Has the Ford F150 Pickup 4WD HEV become more fuel efficient over time?
    Combined MPG has stayed close to flat across the run. Both the earliest (2021 Ford F150 Pickup 4WD HEV, 24 MPG) and most recent (2026 Ford F150 Pickup 4WD HEV, 23 MPG) versions sit in the same range.
  • How much CO₂ does the 2021 Ford F150 Pickup 4WD HEV emit?
    Tailpipe CO₂ emissions are 368 g/mi. Multiplied across a typical year of driving (15,000 miles) that works out to about 5,520 kilograms of CO₂.
  • What is the difference between the city and highway MPG of the 2021 Ford F150 Pickup 4WD HEV?
    City driving returns 24 MPG and highway driving returns 24 MPG. A flat (or city-better) split is the signature of a hybrid or electric drivetrain, where regenerative braking recovers energy that would otherwise be lost in stop-start city traffic.
  • What engine is in the 2021 Ford F150 Pickup 4WD HEV?
    The 2021 Ford F150 Pickup 4WD HEV has a 3.5-liter 6-cylinder turbocharged engine (EPA description: SIDI; Hybrid).
  • What transmission and drivetrain does the 2021 Ford F150 Pickup 4WD HEV have?
    The 2021 Ford F150 Pickup 4WD HEV comes with a automatic (s10) transmission and part-time 4-wheel drive.
  • Is the 2021 Ford F150 Pickup 4WD HEV the most efficient car in its class?
    Yes. Among cars in the Standard Pickup Trucks 4WD class for the 2021 model year, the Ford F150 Pickup 4WD HEV returns the highest combined MPG at 24 MPG. No other car in the same class beats that figure.

Source: U.S. EPA fuel economy dataset. Annual fuel cost figures assume 15,000 miles of driving per year and a 55% city, 45% highway split. Real-world mileage varies with driving conditions, vehicle maintenance, fuel quality, and driver behaviour.