This page collects every fuel-economy figure the EPA publishes for the 2022 Cadillac CT5. Below you will find the headline combined, city, and highway MPG, the estimated annual fuel cost at three different driving levels, the tailpipe CO₂ emissions, and a full breakdown of the engine and drivetrain. The EPA rates 2 separate variants of this car (different engine, transmission, or drivetrain combinations), and you can compare them side by side in the trims table. If you want to know whether this generation got more or less efficient over the years, the year-over-year table further down covers every model year the EPA has rated.

Key takeaways

  • Returns 23% worse combined MPG than the average car in the Midsize Cars class for the 2022 model year (35.2 MPG class average).
  • The most efficient car in the Midsize Cars class for the 2022 model year is the Tesla Model 3 RWD at 132 MPG.
  • EPA estimates this car costs around $2,000 more in fuel over five years than an average new vehicle of the same model year.
  • Requires premium gasoline, which typically adds about 40 to 60 cents per gallon to the EPA's annual fuel cost estimate.

Fuel economy at a glance

These are the EPA's official ratings for the 2022 Cadillac CT5. The numbers come from a standardised laboratory test cycle and are the same figures that appear on the window sticker of every new car. Real-world mileage varies with driving style, weather, fuel quality, and how heavily loaded the car is.

When the EPA tests several variants of the same nameplate (for example, a front-wheel-drive version and an all-wheel-drive version), each gets its own rating. The figures shown here are the headline variant, taken as the configuration with the best combined MPG. The trims table further down covers all 2 variants side by side.

Combined MPG is a 55/45 weighted blend of the city and highway test cycles. The EPA uses it as the single number you can compare across the entire dataset, including hybrids and EVs (which use the equivalent MPGe figure).

Combined MPG 27 MPG
City MPG 23 MPG
Highway MPG 33 MPG
Annual fuel cost $2,550
Tailpipe CO₂ 333 g/mi
Fuel type Premium

How the 2022 Cadillac CT5 compares

The 2022 Cadillac CT5 returns 27 combined MPG. Cars in the Midsize Cars class for the same model year average 35.2 MPG, which puts this car behind the class average by about 23%.

The most efficient car in the Midsize Cars class for the 2022 model year is the Tesla Model 3 RWD at 132 MPG. The bar chart below puts the Cadillac CT5 alongside the class best and the class average so you can see the full picture.

For broader context, the average new car of the 2022 model year (across all classes) returns 30.7 MPG. Larger vehicles pull the all-cars average down, so do not use that figure on its own to judge a small car or a hybrid. The full list of the most efficient cars of the 2022 model year is on its own page.

2022 Cadillac CT5
27 MPG
Class average, 2022
35.2 MPG
Class best, 2022
132 MPG
Average new car, 2022
30.7 MPG

Trim variants rated for 2022

The EPA rates 2 separate variants of the 2022 Cadillac CT5. The differences come from the engine size, transmission type, and drivetrain (front-wheel drive, all-wheel drive, and so on). The same nameplate can land several MPG apart depending on the configuration you actually buy.

The most efficient configuration on this page returns 27 MPG, while the least efficient returns 22 MPG. That is a spread of 5 MPG between trims of the same nameplate.

Engine and transmission Drive Combined City Highway Annual cost
2L, 4-cyl, turbo, Automatic (S10) Rear-Wheel Drive 27 MPG 23 MPG 33 MPG $2,550
3L, 6-cyl, turbo, Automatic (S10) Rear-Wheel Drive 22 MPG 19 MPG 27 MPG $3,150

Annual fuel cost across driving patterns

The headline annual fuel cost the EPA publishes assumes 15,000 miles of driving per year and a fuel mix of 55% city and 45% highway. The dollar figure is calculated using the EPA's current reference price for premium gasoline, which is $4.61/gallon. EPA updates that reference periodically rather than tracking live pump prices, so treat it as a window-sticker estimate rather than today's pump number.

The table below scales the EPA's number to three common driving patterns. The combined MPG and the reference fuel price stay constant, only the annual mileage changes. To get a current-prices estimate, take your local gas price and multiply by 555.6 gallons (the car's annual consumption at the rated MPG).

Driving pattern Estimated annual fuel cost
Light driver, 7,500 miles per year $1,275
Average driver, 15,000 miles per year $2,550
Heavy driver, 25,000 miles per year $4,250

Year-over-year MPG for the Cadillac CT5

The EPA has rated the Cadillac CT5 across 7 model years, from 2020 Cadillac CT5 through 2026 Cadillac CT5. The numbers below are the best combined MPG figure the EPA published for each year, which lets you see when the car was at its most efficient and how recent generations stack up.

Combined MPG has stayed in roughly the same range across the run. The peak rating came with the 2022 Cadillac CT5 at 27 MPG.

Year Combined MPG Open year page
2026 26 MPG 2026 Cadillac CT5
2025 26 MPG 2025 Cadillac CT5
2024 27 MPG 2024 Cadillac CT5
2023 27 MPG 2023 Cadillac CT5
2022 27 MPG this page
2021 26 MPG 2021 Cadillac CT5
2020 26 MPG 2020 Cadillac CT5

Compare against other Midsize Cars for 2022

If you are cross-shopping the 2022 Cadillac CT5, the most useful comparison is against the other cars in the Midsize Cars class for the same model year. The list below shows the highest-MPG peers, ranked from most to least efficient. Click any of them to open its full page.

The Tesla Model 3 RWD leads this group at 132 MPG, 105 MPG ahead of the 2022 Cadillac CT5.

Specifications

The 2022 Cadillac CT5 runs a 2-liter 4-cylinder turbocharged engine paired with a automatic (s10), sending power through rear-wheel drive.

Engine, transmission, and drivetrain together drive most of the variation in fuel economy across trims. A larger engine moves the car with less effort but burns more fuel. A turbo lets a small engine punch above its weight, often without much MPG penalty. All-wheel drive adds traction and weight, and usually costs a couple of MPG compared with two-wheel drive of the same engine.

Vehicle class
Midsize Cars
Engine
2L 4-cylinder turbocharged
Transmission
Automatic (S10)
Drivetrain
Rear-Wheel Drive
Fuel type
Premium
Annual petroleum use
11 barrels per year
Start-stop system
Yes

Common questions about the 2022 Cadillac CT5

Quick answers to the questions people most often search for when looking up the 2022 Cadillac CT5.

  • Is the 2022 Cadillac CT5 fuel efficient?
    Not particularly. The 2022 Cadillac CT5 returns 27 combined MPG, which trails the average car in the Midsize Cars class for the same model year by about 23%.
  • What MPG does the 2022 Cadillac CT5 get?
    The EPA rates the 2022 Cadillac CT5 at 27 combined MPG, 23 MPG in city driving, and 33 MPG on the highway. Real-world numbers depend on your driving style, the weather, and how loaded the car is.
  • How much does it cost to fuel a 2022 Cadillac CT5 per year?
    The EPA estimates an annual fuel cost of $2,550 for the 2022 Cadillac CT5. That figure assumes 15,000 miles of driving per year, a 55% city and 45% highway split, and the EPA's published average fuel price for the rated fuel grade.
  • Does the 2022 Cadillac CT5 require premium gas?
    Yes. The EPA lists the 2022 Cadillac CT5 as requiring premium gasoline. Running it on regular can reduce performance and may affect engine warranties, so it is not a recommended way to save at the pump.
  • Has the Cadillac CT5 become more fuel efficient over time?
    Combined MPG has stayed close to flat across the run. Both the earliest (2020 Cadillac CT5, 26 MPG) and most recent (2026 Cadillac CT5, 26 MPG) versions sit in the same range.
  • How much CO₂ does the 2022 Cadillac CT5 emit?
    Tailpipe CO₂ emissions are 333 g/mi. Multiplied across a typical year of driving (15,000 miles) that works out to about 4,995 kilograms of CO₂.
  • What is the difference between the city and highway MPG of the 2022 Cadillac CT5?
    City driving returns 23 MPG and highway driving returns 33 MPG, a gap of 10 MPG. A spread that wide is typical of cars with conventional automatic or manual transmissions, where stop-start city traffic eats more fuel than a steady highway cruise.
  • What engine is in the 2022 Cadillac CT5?
    The 2022 Cadillac CT5 has a 2-liter 4-cylinder turbocharged engine (EPA description: SIDI). Smaller turbocharged engines like this one tend to deliver bigger-engine power on demand while keeping fuel economy closer to a non-turbo version of the same displacement.
  • What transmission and drivetrain does the 2022 Cadillac CT5 have?
    The 2022 Cadillac CT5 comes with a automatic (s10) transmission and rear-wheel drive.
  • How does the 2022 Cadillac CT5 compare to the best car in its class?
    The most efficient car in the Midsize Cars class for the 2022 model year is the Tesla Model 3 RWD at 132 combined MPG. The Cadillac CT5 returns 27 MPG, a gap of 105 MPG. If you are comparing on fuel economy alone, the class leader is worth a look.

Source: U.S. EPA fuel economy dataset. Annual fuel cost figures assume 15,000 miles of driving per year and a 55% city, 45% highway split. Real-world mileage varies with driving conditions, vehicle maintenance, fuel quality, and driver behaviour.