Pick a year below to open the full Audi S4 page for that model year. Each year page covers combined, city, and highway MPG, the trim variants the EPA rates separately, the annual fuel cost across three driving patterns, and a year-over-year comparison so you can see whether the car has improved.

Fuel economy by model year

Combined MPG, city MPG, highway MPG, and the EPA's estimated annual fuel cost for every model year of the Audi S4. Click any year to see the full breakdown for that model year, including trim variants, the drivetrain, and a comparison against other vehicles in its segment.

Year Model Combined MPG City Highway Annual fuel cost
2025 2025 Audi S4 24 MPG 20 MPG 29 MPG $2,900
2024 2024 Audi S4 24 MPG 21 MPG 29 MPG $2,900
2023 2023 Audi S4 24 MPG 21 MPG 30 MPG $2,900
2022 2022 Audi S4 24 MPG 21 MPG 30 MPG $2,900
2021 2021 Audi S4 23 MPG 20 MPG 28 MPG $3,000
2020 2020 Audi S4 23 MPG 20 MPG 27 MPG $3,000
2019 2019 Audi S4 24 MPG 21 MPG 30 MPG $2,900
2018 2018 Audi S4 24 MPG 21 MPG 30 MPG $2,900
2016 2016 Audi S4 21 MPG 18 MPG 28 MPG $3,300
2015 2015 Audi S4 21 MPG 18 MPG 28 MPG $3,300
2014 2014 Audi S4 21 MPG 18 MPG 28 MPG $3,300
2013 2013 Audi S4 21 MPG 18 MPG 28 MPG $3,300
2012 2012 Audi S4 21 MPG 18 MPG 28 MPG $3,300
2011 2011 Audi S4 21 MPG 18 MPG 28 MPG $3,300
2010 2010 Audi S4 21 MPG 18 MPG 28 MPG $3,300
2008 2008 Audi S4 16 MPG 14 MPG 21 MPG $4,300
2007 2007 Audi S4 16 MPG 14 MPG 21 MPG $4,300
2006 2006 Audi S4 16 MPG 13 MPG 20 MPG $4,300
2005 2005 Audi S4 16 MPG 13 MPG 20 MPG $4,300
2004 2004 Audi S4 18 MPG 16 MPG 22 MPG $3,850
2002 2002 Audi S4 18 MPG 15 MPG 22 MPG $3,850
2001 2001 Audi S4 18 MPG 15 MPG 22 MPG $3,850
2000 2000 Audi S4 18 MPG 15 MPG 22 MPG $3,850
1994 1994 Audi S4 18 MPG 16 MPG 22 MPG $3,300
1993 1993 Audi S4 18 MPG 16 MPG 22 MPG $3,850
1992 1992 Audi S4 18 MPG 16 MPG 22 MPG $3,850

How the Audi S4 compares against the Compact Cars class

Buyers usually compare the Audi S4 against other cars in the same EPA class. The list below shows the most efficient cars in the Compact Cars class for the 2025 model year, the latest year on this page. Each link opens the full page for that car.

Source: U.S. EPA fuel economy dataset. Annual fuel cost assumes 15,000 miles of driving per year and a 55% city, 45% highway split.